The patient was a 66-year-old woman. PET-CT performed during the treatment of lung cancer showed FDG accumulation in the appendix. Colonoscopy showed submucosal elevation and erythematous orifice of the vermiform appendix, and contrast-enhanced CT showed wall thickening and contrast effect at the same site. The resected specimen showed wall thickening of the appendix. Histologic findings showed fissuring, transmural inflammation, and epithelioid cell granuloma.We diagnosed isolated Crohnʼs disease of the appendix. There has been no recurrence 6 months after surgery. Isolated appendiceal Crohnʼs disease without preceding bowel symptoms is a rare and diagnosis is difficult. We report this of Crohnʼs disease of the appendix with a review of the literature.

A71-year-oldwomanunderwentpartialmastectomyforleftbreastcancer(T1bN0M0).Sherefused adjuvanttherapyandhadbeenfollowedupwithouttreatments.Threeyearsandfivemonthsafterthe surgery,metastasistotheleftaxillarylymphnodeandmultiplebonemetastaseswereobserved,andfurther three months later dyspnea appeared. A chest computed tomography showed multiple infiltrative andfrostedshadowsinbothlungs,atransbronchiallungbiopsyshowedtumorembolizationintheblood vessels,andanechocardiographyshowedrightheartfailure.Wesuspectedpulmonarytumorthrombotic microangiopathy (PTTM) and continued anticoagulant therapy, but the condition took a progressive downhillcourseandthepatientdiedonthe20thhospitalday.CliniciansshouldconsiderPTTMasadifferentialdiagnosisinpatientswithcancerwhodevelopprogressivedyspneaandrightheartfailure.