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We herein prepared defectiveB i 2 O 2 CO 3 microspheres via a simple nitric acidt reatment method. Upon generation from Bi 2 O 2 CO 3 ,e lectrons andh oles were superbly separatedw ith the existence of defects. Combined with the advantages of multiple scattering and reflection,alarge surface area and increasedr ange of visible-light absorption, the defective Bi 2 O 2 CO 3 dispalyed ah igh efficiency for the photodegradation of HCHO gases and methyl orange. The defective Bi 2 O 2 CO 3 also possessedasuperiors tability,w hichi si mportant for practical applications. Thisw ork opens up new opportunities for the design and fabrication of high-activity Bi-based photocatalysts for environmental protection.The authors declare no conflict of interest. Figure 4. (a) EISN yquist plots, (b) Transient photocurrent densities under visible-lightirradiation, (c) Photoluminescences pectra upon excitation at 300 nm, and (d) Nanosecond-levelt ime-resolved fluorescencespectrao fa ll the samples. (e) The proposed migrationm echanism of photoelectronsa nd holes.

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Atomically thin two‐dimensional semiconductors provide an ideal platform to establish clear structure‐property relationships in the field of photocatalysis. Herein, we fabricated the atomically thin Bi2MoO6 nanosheets by a facile and scalable wet‐chemical synthesis approach. Oxygen vacancies were inevitably induced into the nanosheets as the thickness of the nanosheets exposed interior atoms, which are clearly identified by X‐ray photoelectron spectroscopy (XPS) and electron paramagnetic resonance (EPR) spectra. More intriguingly, the oxygen vacancies formed on the open interfaces could enhance charge transport, further improving the photocatalytic performance. Benefiting from the large surface areas and increased visible light absorption, the present atomically thin Bi2MoO6 nanosheets display extraordinary high‐performance of photocatalytic degradation of phenol and cycling stability. More importantly, we believe that this achievement in ultrathin two‐dimensional material (atomically thin Bi2MoO6 nanosheets) could bring new insights into designing high‐performance photocatalysts.

Introduction TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) can induce apoptosis in a variety of cancer cells. However, drug resistance of tumor and short half-life seriously affects its clinical targeted therapy. Cabazitaxel (CTX) is a taxane drug, which can induce apoptosis or autophagy by inhibiting the phosphorylation of PI3K/Akt/mTOR and sensitive to some drug-resistant tumors. Therefore, we explored the possibility of developing a mesenchymal stem cell-derived exosomes (MSC-EXO) vector for oral squamous cell carcinoma (OSCC) to deliver CTX/TRAIL combinations. Methods After ultracentrifugation and dialysis, CTX/TRAIL loaded exosomes transfected MSC (MSCT)-derived exosome (EXO) (MSCT-EXO/CTX) were isolated and purified. The expression of CD63, CD9 and TRAIL was detected by BCA to confirm the origin of EXO. High-performance liquid chromatography (HPLC) was used to determine the drug loading of VPF and draw the in vitro release profile. MTT assay, flow cytometry and Western blot were used to detect the antitumor effect of MSCT-EXO/CTX in vitro. Subsequently, the antitumor effect of MSCT-EXO/CTX in vivo was verified by mouse model. Results The diameter of the membrane particles was about 60–150 nm. We have proved that the incorporation and release of CTX in MSCT-EXO can inhibit the activation of PI3K, Akt and mTOR, which is a possible synergistic mechanism of CTX. MSCT-EXO and CTX can induce the apoptosis of SCC25 tumor cells in a dose-dependent manner and exert a good synergistic effect in the proportion range of 10:1–5:1. The inherent activity of MSCT-EXO and the direct effect of MSCT-EXO/CTX on OSCC confirm that MSCT-EXO/CTX makes MSCT-EXO and CTX have an efficient synergistic effect and a highly effective pharmacological inhibition on cancer cells, as verified by the subsequent mouse model. MSCT-EXO/CTX showed the lowest relative tumor volume and the highest tumor inhibition rate (P<0.05) in vivo. Conclusion An MSCT-EXO-based CTX delivery system might be an effective anticancer method.