Ставропольский государственный медицинский университет, российская Федерация 2 Городская детская клиническая больница им. Г. К. Филиппского, Ставрополь, российская Федерация Celiac disease is one of the multisystem autoimmune diseases that is being intensively studied due to the very widespread prevalence in almost all regions of the world and extremely adverse effects on the health and quality of life of patients. Timely detection of celiac disease is a problem for many physicians due to the variety of clinical manifestations, the erased, lowsymptom and atypical course of the disease. Screening of celiac disease in groups of genetic risk is recognized as one of the methods of primary prevention of autoimmune and oncological diseases.