Abstract. Coordinate measuring machine (CMM) is a device used to measure physical geometry of object. It has been used widely in industry for quality control and monitoring of production process due to its high accuracy and precision. Measurement accuracy is very crucial in quality inspection as measurement result is used to decide if the product should become defect. CMM accuracy depends on several factors such as probe size, number of touching point and measurement speed. This research applied design of experiment technique to optimize setting of those parameters to obtain high measurement accuracy. A case study from swage hole measurement of hard disk drive actuator arm was use to demonstrate the proposed technique. The result showed that CMM accuracy of the case study company was significantly increased after CMM has been set with parameters optimized with design of experiment.