Introduction
The purpose of this study was to test the short-term efficacy of four commercial mouthwashes versus water in reducing SARS-CoV-2 viral load in the oral cavity over clinically relevant time points.
Methods
In total, 32 subjects that were proven SARS-CoV-2-positive via polymerase chain reaction (PCR)-based diagnostic test were recruited and randomised into five parallel arms. Cycle threshold (Ct) values were compared in saliva samples between the groups, as well as within the groups at baseline (pre-rinse), zero hours, one hour and two hours post-rinse, using SARS-CoV-2 reverse transcription-PCR analysis.
Results
We observed a significant increase in Ct values in saliva samples collected immediately after rinsing with all the four mouthwashes - 0.12% chlorhexidine gluconate, 1.5% hydrogen peroxide, 1% povidone iodine, or Listerine - compared to water. A sustained increase in Ct values for up to two hours was only observed in the Listerine and chlorohexidine gluconate groups. We were not able to sufficiently power this clinical trial, so the results remain notional but encouraging and supportive of findings in other emerging mouthwash studies on COVID-19, warranting additional investigations.
Conclusions
Our evidence suggests that in a clinical setting, prophylactic rinses with Listerine or chlorhexidine gluconate can potentially reduce SARS-CoV-2 viral load in the oral cavity for up to two hours. While limited in statistical power due to the difficulty in obtaining this data, we advocate for pre-procedural mouthwashing, like handwashing, as an economical and safe additional precaution to help mitigate the transmission of SARS-CoV-2 from a potentially infected patient to providers.
Preoperative patient evaluation and implant planning are required for dental implant surgery to be predictably successful. This article reviews necessary elements of the implant workup, including reviewing the patient's medical history, performing hard and soft tissue evaluations, and assessing the alveolar ridges and dental arches. In addition, consideration is given to digital implant planning and surgical guide fabrication as means to simulate implant surgery preoperatively and then precisely execute that surgery clinically.
Keywords Dental implants • Planning • Complications • 3D planning • Oral surgery
Quick reference/descriptionThe use of implants and restorative prospects have grown over the years. However, the ever-increasing implant-based rehabilitations have led to increased implant-associated complications and morbidities, most of which occur due to inadequate preoperative evaluation and poorly designed treatment plans. A thorough preoperative work-up and a properly designed comprehensive treatment plan can prevent unrecognized prosthetic or surgical issues.
IndicationsTo prevent unrecognized surgical or prosthetic problems.
The surgical ciliated cyst is an iatrogenic lesion occurring after surgeries in which the Schneiderian membrane has been exposed, such as in orthognathic surgery or maxillary sinus procedures. This lesion has been infrequently documented in western countries. In this case series, we present three cases of surgical ciliated cysts of the maxilla.
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