Utilizing historical clinical datasets to guide future treatment choices is beneficial for patients and physicians. Machine learning and feature selection algorithms (namely, fisher's discriminant ratio, Kruskal-Wallis' analysis, and Relief-f) have been combined in this research to analyse a SeeR database containing clinical features from de-identified thyroid cancer patients. The data covered 34 unique clinical variables such as patients' age at diagnosis or information regarding lymph nodes, which were employed to build various novel classifiers to distinguish patients that lived for over 10 years since diagnosis, from those who did not survive at least five years. By properly optimizing supervised neural networks, specifically multilayer perceptrons, using data from large groups of thyroid cancer patients (between 6,756 and 20,344 for different models), we demonstrate that unspecialized and existing medical recording can be reliably turned into power of prediction to help doctors make informed and optimized treatment decisions, as distinguishing patients in terms of prognosis has been achieved with 94.5% accuracy. We also envisage the potential of applying our machine learning strategy to other diseases and purposes such as in designing clinical trials for unmasking the maximum benefits and minimizing risks associated with new drug candidates on given populations. Machine learning as algorithmic advancement in the past few years dramatically improved our range of potential implementation of artificial intelligence for tasks such as learning and playing the Go game, environment feature recognition for self-driving, and in medical applications 1,2. Within the machine learning scope, artificial neural networks (ANNs) are a set of algorithms that recognize patterns and learn from inputs and outputs to make useful connections without pre-set rules 3. Furthermore, ANNs and their performance correlate well with the training data size and are more adept at pattern recognition and classification when analysing large hospital records than traditional statistical modelling applied in some of the more recent cancer prognostication applications 4,5. ANN models are designed in layers to learn increasingly higher-dimension and remote representations of the input data and devise meaningful outcomes to feed the next layer. In this work, we tested three separate neural network models to determine the outcomes of thyroid cancer patients after diagnosis from distilling the U.S. Surveillance Epidemiology and End Results (SEER) database. Although back in 2015 thyroid cancer cases in the United States were predicted to increase to 92,000 by 2020 6 , and current estimates indicate that in 2019 around 52,000 are projected instead, these numbers still signify that thyroid cancer incidence rates continue to increase 7. Specifically, regarding women, thyroid cancer ranks sixth compared to other types of cancer in terms of incidence with almost 38,000 new estimated cases per year 7. These trends can be mainly attributed to an increase in ...
With the contact-free situation due to the COVID-19 pandemic, many organizations tend to host virtual events instead of conventional offline events. Since many things should be handled through the online operations, the traditional system for offline events should be re-designed to support the whole process of virtual events. In this paper, we propose an architecture of an all-in-one platform for virtual conferences. The platform provides full services required by a virtual conference which is easy enough for both IT and non-IT experts. The platform provides tailored functions and menus according to the specific size, nature, and field of an academic event. Experimental results show that the parallel upload function of the proposed architecture achieves significantly higher upload speed for sharing a presentation video after the recording ends, compared to the usual video upload function.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with đź’™ for researchers
Part of the Research Solutions Family.