Two hundred and ninety-two participants from 126 urban and rural locations across Australia responded to a questionnaire assessing levels of environmental concern and behaviour. The environmental concern items consisted of the Thompson and Barton ecocentric, anthropocentric, and apathy scales, together with the items in the New Ecological Paradigm (NEP) revised scale. The broad picture in terms of sociodemographic variables was that female gender, better education, and being older were associated with higher levels of ecocentric concern for the environment and reporting more ecological behaviours. In regard to concern measures, reported frequency of environmental behaviours was positively associated with levels of ecocentric concern and endorsement of the NEP scale, and negatively associated with levels of anthropocentric concern and apathy. A combination of scores on the Thompson and Barton scales and demographic variables accounted for 36% of the variability in reported ecological behaviours.

Gastric cancer (GC) is the fourth most common cancer in the world with approximately 1 million patients being diagnosed annually and is the second highest cause of cancer related deaths worldwide resulting in 700,000 deaths per year. The advanced stage at diagnosis and limited curative treatments for this stage of disease explains the mortality rate for GC. Early and late GC can usually be differentiated by their T-stage, which is a measure of invasion of the tumour through the gastric wall. T1 tumours exhibit minimal invasion whilst T4 tumours have invaded into adjacent structures. Through our genomic research we have identified SFRP4 as a gene that is consistently over-expressed in gastric cancer when compared to normal gastric tissue, particularly advanced stage cancer. Its gene expression levels are directly proportional to the degree of invasion suggesting a potential role in this process. Analysis of the clinical data in conjunction with the genomics data shows that elevated levels of SFRP4 have also been correlated with poor prognosis in patients with GC independent of their T-stage. We have used shRNA knockdown of SFRP4 in a gastric cell line to validate these findings in vitro. The invasive phenotype is able to be restored in these cells with the addition of recombinant SFRP4 protein. Evidence from this study suggests that SFRP4 plays a role in invasion which is a fundamental property of all cancers. In vivo studies are currently underway to determine whether the functional effects of SFRP4 observed in vitro in gastric cancer lines can be recapitulated in vivo. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2011;71(8 Suppl):Abstract nr 2336. doi:10.1158/1538-7445.AM2011-2336

This study was deemed exempt by the Midwestern University, Institute Review Board, therefore written informed consent was not gathered. Purpose:The devasting effects of the coronavirus disease 2019 (COVID-19) pandemic have warranted the rapid development of evidence surrounding the physical therapy (PT) management of the disease within inpatient settings. However, the medical community is still working to define the long-term effects of COVID-19, referred to as Postacute Sequalae of SARS-CoV-2 (PASC), and ways for physical therapists to manage them in outpatient settings. The primary objective of this review was to summarize the available evidence related to the PT management of PASC in outpatient settings. Methods: A systematic search in PubMed, Cumulative Index to Nursing and Allied Health Literature, Cochrane CENTRAL, Academic Search Complete, and MedLine yielded systematic and scoping reviews and randomized controlled trials, among others. Data extraction was performed independently by 2 reviewers with 8 studies included. Results: Only 3 publications were specific to the outpatient setting area, with 5 more studies that focused on outpatient practice as part of a multisetting study, or the postacute setting. Although the limited number and quality of publications creates challenges applying the interventions provided across a population, each were specific to PASC. Conclusions: This review supports the need for further research focused on the PT management of patients who are experiencing PASC in outpatient settings.

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