POSTERSResults: Activation areas in SD, compared with controls, were in right inferior frontal gyrus, right supramarginal gyrus, right middle temporal gyrus, and right superior temporal gyrus. On the contrary, decreased brain activity in SD group was observed in bilateral primary sensory area, right inferior parietal cortex, bilateral precentral gyrus, bilateral rolandic operculum, bilateral SMA, left anterior cingulate cortex, bilateral middle cingulate gyrus, right temporal pole, right superior pole, bilateral cerebellum, left inferior frontal gyrus, right insula lobe, bilateral thalamus, and right basal ganglia.
Conclusion:The present fMRI study demonstrated that brain activity during phonation in SD resembled those in other local dystonia diseases, especially in sensorimotor area, supplementary motor area, basal ganglia, thalamus, and cerebellum. Although sample size was quite limited, it is likely that spasmodic dysphonia is one aspect of local dystonia.