No abstract

Background: Direct-acting antivirals are highly effective for the treatment of hepatitis C virus (HCV) infection, regardless race/ethnicity. We aimed to evaluate demographic, virological and clinical data of HCVinfected migrants vs. natives consecutively enrolled in the PITER cohort. Methods: Migrants were defined by country of birth and nationality that was different from Italy. Mann-Whitney U test, Chi-squared test and multiple logistic regression were used. Results: Of 10,669 enrolled patients, 301 (2.8%) were migrants: median age 47 vs. 62 years, ( p < 0.001), females 56.5% vs. 45.3%, ( p < 0.001), HBsAg positivity 3.8% vs. 1.4%, ( p < 0.05). Genotype 1b was prevalent in both groups, whereas genotype 4 was more prevalent in migrants ( p < 0.05). Liver disease severity and sustained virologic response (SVR) were similar. A higher prevalence of comorbidities was reported for natives compared to migrants ( p < 0.05). Liver disease progression cofactors (HBsAg, HIV coinfection, alcohol abuse, potential metabolic syndrome) were present in 39.1% and 47.1% ( p > 0.05) of migrants and natives who eradicated HCV, respectively.

No abstract

No abstract

No abstract