It is a well-known verity that many systemic diseases are manifested in the oral cavity. Irrespective of the organ system involved, changes frequently occur in the oral cavity reflecting disease elsewhere in the body. Uremic stomatitis is one such rare oral mucosal disorder associated with end-stage renal failure. Clinically it is characterized by the presence of painful plaques and crusts that are usually distributed on the buccal mucosa, dorsal or ventral surface of the tongue, gingiva, lips, and floor of the mouth. Hence, it is accurately said that oral cavity is the mirror of the general health and treating the underlying disease first followed by local therapy is the way to manage these conditions. Here, we discuss a rare case of a young male patient presenting with oral manifestations of previously undiagnosed renal failure.

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Pyle's disease (PD) or metaphyseal dysplasia is an extremely rare genetic disorder, transmitted as an autosomal recessive trait. The peculiarity of the disease is that the striking radiographic manifestations contrast with the relatively normal clinical features. The oral findings and radiographic features of the disease are not well documented. The present paper describes the radiographic features of Pyle's disease in a 17-year-old girl and draws attention to the findings in the jaw bones.

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