Sendai virus irradiated by UV light, the dose of which is sufficient for inactivation of infectivity, is capable of inducing synthesis of early protein only. The synthesis of early virus-specific proteins was observed in the absence of virusspecific RNA-synthesis. Consequently, RNA of virion (plus-strand) is the m-RNA for the synthesis of early virus-specific proteins of Sendal virus. Since viral structural proteins do not synthesize under these conditions, it is assumed, that the synthesis of virus capsid proteins is coded by a minus-strand. The possible significance of such processes for an understanding of the nature of viral oncogenesis and stable antiviral immunity is discussed. 21"

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