The species Sanguisorba officinalis L. is widespread in the Republic of North Ossetia-Alania and is promising for the study and practical use of the pharmacological and food industry. The aim of the work is to analyze the dynamics of biologically active substances in the phytomass S. officinalis depending on the altitude gradient under conditions of RNO-Alania. Studies were carried out in 2012-2016. Samples of vegetable raw materials were taken at 5 stationary points located in various high-altitude belts: 1079, 1480, 1760, 1810 and 2300 m above the sea level. Studies were conducted using standard methods. The air-dry yield of S. officinalis above-ground phytomass in an averaged between 0.669 to 1.05 kg/m 2 over the years of research. The content of the studied biologically active substances in the above-ground phytomass of S. officinalis was found to change with increasing growth height. At a height of 1079 m, a high content of nitrogen-free extractive substances, hydroxycoric acids (in terms of chlorogenic), leukoantocyans, catechins, tanning substances was found in tissues. At a height of 1480 m, the accumulation of crude protein and routine was observed. At an altitude of 1810 m, fiber, ash elements, ascorbic acid, saponins (in terms of ursolic acid), and carotenes accumulate in grass. At a height of 2300 m, plant tissues show maximum levels of crude fat and flavonoids. The obtained data make it possible to estimate antioxidant and P-vitamin properties of S. officinalis and to recommend collection of vegetable raw materials of S. officinalis at different height to obtain certain biologically active substances. Effective and low-toxic natural polyphenolic antioxidants of S. officinalis can be used in the food, cosmetic and pharmaceutical industries.

The need for a systematic phytochemical studying of Nepeta cataria L. is related to solving the problem of using of this valuable plant resource. The purpose of the work was to study the dynamics of the accumulation of biologically active substances in the aboveground phytomass of N. cataria L. in the Republic of North Ossetia-Alania. In years 2008-2013 the study of N. cataria L. was carried out in a culture on the basis of standard methods. The aboveground phytomass of N. cataria L. contains a variety of biologically active substances. A study of the dynamics of the content of the main biologically active substances in ontogenesis showed that during mass flowering, the maximum content is reached for essential oils, total acidity, ascorbic acid, and the content of tannins. The content of individual biologically active substances did not depend on the ontogenesis phase and remained at the same level during the growing season. There was established the relationship between the biologically active substances content and the weather and climate conditions of the year: directwith average air temperature and inversely proportionalto the amount of precipitation. Keywords-Nepeta cataria L., phenological phases of development, biologically active substances, antibacterial activity I.A systematic phytochemical study of N. cataria L. is necessary in order to solve the problem of using this valuable 1st International Symposium Innovations in Life Sciences (ISILS 2019)

Результаты изучения биологии развития шалфея мутовчатого Salvia verticillata L. и шалфея мускатного S. sclarea L. в условиях Республики Северная Осетия-Алания показали, что виды характеризуются высокой продуктивностью надземной массы и семян. Накопление биологически активных веществ в биомассе S. verticillata и S. sclarea оценивали в зависимости от фазы вегетации. Содержание эфирных масел было максимально в фазе массового цветения: от 0.5 до 0.7 % у шалфея мутовчатого, от 0.5 до 0.6 % у шалфея мускатного. Содержание аскорбиновой кислоты было максимально в фазе бутонизации: от 68.4 до 77.2 % у шалфея мутовчатого и от 65.2 до 73.5 % у шалфея мускатного. Установлено, что максимальное количество флавоноидов накапливается в фазу цветения.

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