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Background: Developmental care for premature infants can be defined as all techniques that are not pharmacological, behavioral and environmental, to support its development in its neurological, behavioral, relational and cognitive components. The purpose of our study was to assess the impact of its developmental care in our service. Materials and patients:This is a prospective comparative analytical study that took place between October 2016 to September 2017. Children born before 37 weeks of Amenorrhea (GA) were included with a birth weight less than or equal to 1500 g. Results:Our study recorded 180 mother children including 100 with permanent accompaniment and 80 without permanent accompaniment. The average gestational age was 32.68±2.6, the pregnancy was followed in 15.9%, the average birth weight was 1450±40. Skin to skin was practiced in 55% of cases. The mean discharge weight was 1692, 70±533 for those with permanent parental guidance, and 1515±25 for those without. Median duration of hospitalization was more important in those who did not receive permanent support p (0.03). A statistically significant positive correlation was observed between the rate on apnea and skin to skin practice, it was the same for the rate of hypothermia. Conclusion:Developmental care represents a new standard of care in neonatology of scientifically proven efficacy. Several elements supporting the importance of developmental care practices provided to the premature child have been clearly identified. They are essentially based on information and education of parents, training and support of health care team; if this practice has shown its effectiveness in developed countries, it is crucial to integrate it into neonatal care in our country. It will help to alleviate the lack of beds of neonatology for low birth weight.