клиническая гастроэнтерология | clinical gastroenterology Резюме В последние годы возрастает внимание к оценке роли микробиоценоза кишечника в развитии сердечно-сосудистых заболеваний, в том числе артериальной гипертензии (АГ) и метаболического синдрома (МС), отдельные компоненты которого в той или иной степени связаны с состоянием микробиоты. В связи с этим нами была предпринята попытка уточнить особенности микробиоты кишечника у пациентов АГ на фоне МС в сравнительном аспекте с таковыми при изолированно протекающей АГ. Проведено микробиологическое исследование фекалий у 86 больных, из них 46с АГ (группа сравнения) и 40 -с АГ и МС (основная группа). Микробиоту фекалий исследовали с помощью классического бактериологического метода и биохимического метода экспресс-диагностики дисбактериоза. Для фекальной микробиоты при АГ с МС, по сравнению с АГ, характерно более низкое выделение представителей нормальной микрофлоры (бактероиды, лактобациллы, бифидобактерии) за исключением кишечной палочки, более частое выделение факультативной микрофлоры (энтерококки, клебсиеллы, пептострептококки, стафилококки, протеи и др.), II и III степени дисбактериоза (против I и II при АГ). В результате исследования выявлено, что состав микробиоты кишечника у больных АГ ассоциирован с МС как в плане уменьшения отдельных представителей нормальной микрофлоры, так и большего присутствия или появления новых представителей условно-патогенной микрофлоры с формированием высокой степени дисбактериоза.Ключевые слова: артериальная гипертензия, метаболический синдром, микробиота кишечника Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.

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The research work is devoted to the obtaining of food fibres enriched in b-carotene. Specially prepared wheat bran (45mcm fraction) served as a base. b-carotene solution has been sprayed on the bran. The food additive obtained can be used for pretreatment and complex treatment of several diseases, correction of immunodeficiency and vitamin insufficiency compensation. 30 832 7663 A novel processing concept based on the application of high pressure technology in food sterilization is introduced. Generated heat of compression during pressure build-up step combined with a reduced resistance of Bacillus stearothermophilus spores in particular pressure/temperature conditions is utilized to rapidly elevate the temperature in the centre of immiscible food products. During this process the same lethal effect compared to the classical pathway of sterilizing is achieved. This volumetric heating together with the rapid decrease of temperature during the decompression step allows to effectively inactivate spores which are hazardous in food canning industry. Quality loss, as an undesirable side-effect, which is attributed to heat transfer limitations in conventional processing, is strongly reduced by the proposed process. 360* Development of a Measuring System for Microwave Dielectric Properties at 2.45 GHz R e g i e r , M . F r i t z , P . S c h u b e r t , H .

The combined course of arterial hypertension (AH) and metabolic syndrome (MS) leads to an increased risk of cardiovascular complications, type 2 diabetes mellitus and overall mortality. Psychological factors play an important role in the emergence and development of hypertension and MS. Affective mental disorders and psychosocial stress can aggravate the course of this pathology, reducing the quality of life of patients. Purpose of the study. To study the effect of MS on the mental state and quality of life in patients with hypertension based on the results of psychodiagnostic testing. Materials and methods. 120 outpatients were examined. The 1st group (comparison) included 63 patients with AH, the 2nd (main) group included 57 patients with AH and MS. The following scales were used: psychosocial stress scale of L. Rieder et al., Hospital Anxiety and Depression Scale (HADS), Abbreviated Multifactor Personality Questionnaire (SMOL), Quality of Life Scale (SF-36). Results. The frequency of psychosocial stress in AH with MS was 93%, and in AH it was 67% (p < 0.001). High stress was 2 times more common in AH patients with MS than in AH patients. Anxiety disorders were detected in 72%, and depressive disorders in 79% of AH patients with MS, which is much more common than in AH patients. Quality of life indicators on a number of scales of physical and mental components of health were lower in AH with MS than in AH. Conclusion. The data obtained indicate a significant deterioration in mental health and quality of life in patients with hypertension on the background of MS.