No abstract

This study compares the growth of babies randomised to receive one of three methods of feeding: hourly bolus nasogastric feeding (bNG), continuous nasogastric feeding (cNG) and continuous transpyloric feeding (TP).

Copper and very low birthweight babies 81 Current recommended doses range from 010- iimol/kg/day,4 5 and some recommend that copper be excluded completely from short term parenteral nutrition.6 Our experience suggests that potentially toxic concentrations of copper can be achieved in critically ill preterm infants and that intravenous copper supplements should be withheld until the babies are stable, and then their serum copper concentrations should be monitored. Further studies are needed to define optimal intravenous copper requirements.

We report a growth-retarded infant with congenital heart disease and maternal isodisomy for chromosome 16. Non-mosaic trisomy 16 was detected at mid-trimester chorionic villus sampling, performed because biochemical screening indicated an increased Down's syndrome risk. Further karyotyping analysis of the placenta, after delivery, showed a 50 per cent mosaic trisomy 16. The infant had an atrioventricular (A-V) canal defect, scoliosis, and several minor dysmorphic features. Although uniparental disomy for chromosome 16 has been reported previously, to our knowledge this is the first case of uniparental isodisomy for chromosome 16 which has been investigated with multiple DNA probes.

No abstract