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Two patients (a 16-month-old boy and a 53-year-old man) were referred for MR imaging of a small, subcutaneous nodule at the forearm. Plain films were available in one patient and showed a non-specific well-circumscribed lesion. Upon ultrasonography (1 patient), a nodular, well-circumscribed, hyperechoic lesion was seen. In both cases spin-echo (SE) T1-weighted images (T1WI) showed homogeneous, intermediate signal intensity (SI). On gadolinium-enhanced T1WI (1 patient), no enhancement was observed. Both lesions showed predominant low-to-intermediate SI on T2WI. At histological examination characteristic findings of pilomatricoma were observed.

A case of a chondrosarcoma in a patient with relapsing polychondritis was presented. The association of these two unusual disorders of cartilaginous tissue has never been described before. The clinical presentation and radiologic and histologic features were discussed.

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