The occurrence of metastatic tumours in the breast is uncommon and it is crucial for cytologists to be aware and distinguish them cytologically from primary breast tumours in fine needle aspirates. In the present retrospective study of 11 cases, over a 20‐year period, we discuss the cytological features of extramammary metastatic tumours in the breast. A brief attempt has been made to discuss the past literature. The 11 metastatic tumours included four haematolymphoid neoplasms, two melanomas, two metastatic sarcomas and three metastatic carcinomas. A prior clinical diagnosis of the primary tumour was obtained in seven cases. Immunohistochemistry or histology following a cytological diagnosis confirmed all the cases. The main objective of this study was to highlight the use of cytology and at the same time caution the cytologist to be aware of the clinical/imaging findings and if necessary to utilize immunohistochemical facilities to consider/rule out the possibility of metastatic tumour in the breast.
In 11 patients with severe angina pectoris a newblocking drug, atenolol (Tenormin; I.C.I. 66082), was found in a double-blind randomized trial to reduce significantly the frequencyofanginal attacks (P <0 001) and the amount of trinitrin consumed (P <0 03) in comparison with practolol and placebo. There was no significant improvement in the patients' ability to exercise on thebicycleergometer.
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