Annotation. The military events in Ukraine (2022-2023 years), the economic and social changes closely related to them led to an increase in the level of social tension, social anxiety, and the appearance of stress among the Ukrainian population. The purpose of this study is to assess level of anxiety, depression and stress in Ukrainian medical students. The DASS-21 questionnaire (Ukrainian language version) was used to investigate 374 medical students of the II-III years of study in Vinnytsya National Medical University (the average age 19.47±0.11 years, boys – 148, girls – 226). Testing was carried out in the territory where there are no military operations, in the non-sessional period. The test results were statistically processed using the statistical analysis package of the Microsoft Excel program. It was found that there are only 67 medical students who have normative values of the DASS-21 test (17.91±1.98%). Depression of varying degrees (from mild to very severe) occurs in 198 (52.94±2.58%) students, stress is detected in 190 (50.80±2.59%) people, and anxiety in 240 (64.17±2.48%). Statistically significant gender differences in the results of the DASS-21 test are observed, in particular, the percentage of people with depression, anxiety and stress among women is higher than among guys (respectively, p˂0.001, p˂0.001, p˂0.01), female students probably more often (compared to boys) feel depressed and moody (p˂0.001), terrified (p˂0.01), close to panic (p˂0.001), or they are disturbed by situations that can cause panic or lead to deception (р˂0.001), they spend a lot of nervous energy (р˂0.001), feel low self-esteem as individuals (р˂0.01), loss of initiative (р˂0.05), the ability to feel something positive in general (p˂0.05), are too sensitive (p˂0.001), worried, excited (p˂0.01). Thus, in the difficult socio-economic conditions of the military conflict between Russia and Ukraine, there is widespread depression, anxiety and stress among students, studying in a higher medical institution in Ukraine, not in a combat zone. It is advisable to analyse the strategies for getting out of stressful situations used by modern students, assess their suicidal risks, and widely promote psycho-relaxing techniques and the most optimal strategies for overcoming stress among medical students.

According to many studies, the rheovasographic index of the thighs can detect slight changes in the vessels, do not constitute a critical inconvenience, but in advance indicate that more serious diseases of the lower limb are approaching. The purpose of the study is to determine the age and gender features of thigh rheogram indicators in practically healthy adolescents in the Podillia region of Ukraine. The rheographic parameters of the thighs of 103 practically healthy boys aged from 13 to 16 years old and 108 girls aged from 12 to 15 years, urban residents of the Podillia region of Ukraine, were determined using a cardiology computer diagnostic complex. The statistical processing of the obtained results was carried out in the license package “Statistica 5.5” using parametric and nonparametric methods for evaluating the obtained results. In 12-year-old girls, in comparison with other age groups, it was found that most of the amplitude indices (with the exception of the incisura amplitude), the time of the downstream part of the rheogram and the average speed of fast and slow blood flow are significantly higher, while the time of the rising part of the rheogram and fast and slow blood overflow and thumb vascular tone rates in most cases are significantly lower. In most cases, 13 and 14-year-old boys, compared to 15 and 16-year-old adolescents, the basic impedance and amplitude of the systolic wave, as well as most vascular tone rates and average slow-blood flow rates are significantly higher or tend to be higher. It has also been found that most of the time indicators (with the exception of slow blood flow time) in 14-year-old boys are significantly lower or tend to be lower than in other age groups of boys. When comparing rheogram data between boys and girls according to the calendar and biological age, the majority of amplitude and derivative indices, as well as the time of slow blood filling in 14 and 15-year-old girls, are significantly higher in girls. Boys have significantly higher values of the duration of the cardiac cycle and the time of the downstream part of the thigh rheogram, as well as all time and most indicators of vascular tone in 13-year-old boys than in 12-year-old girls. Thus, the expressed age and gender differences in the rheogram data of the thigh in practically healthy adolescents have been established.

Norms for assessing the functional state of the peripheral vascular system are developed, as a rule, without regard to age, gender and somatotype. The purpose of the study is to establish features of the indicators of crus rheogram in practically healthy girls and boys of different somatotypes, residents of the Podillia region of Ukraine. Rheographic indicators of the cohort of 108 practically healthy girls aged from 12 to 15 years old and 103 boys aged from 13 to 16 years and 103, urban residents of the Podillia region of Ukraine, were determined using a cardiology computer diagnostic complex. Anthropometric survey was conducted in accordance with the scheme of V. V. Bunak (1941). To evaluate the somatotype of adolescents, the mathematical scheme of J. Carter and B. Heath (1990) was used. The statistical processing of the obtained results was carried out in the license package "Statistica 5.5" using nonparametric methods for evaluating the obtained results. As a result of the research, it was found that most of the amplitudes and some of the derived indicators of the crus rheogram in girls of the mesomorphic somatotype are significantly lower or tend to be smaller than those of other somatotypes, while the time of the rising part of the rheogram and the time of slow blood filling are significantly higher than at representatives of an ectomorphic somatotype. In boys of mesomorphic somatotype, the basic impedance and amplitude of the systolic wave and the average speed of fast and slow blood flow of the rheogram are significantly lower or tend to be lower than those of other somatotypes, while the time of the ascending part and fast blood flow of rheograms and the diastolic index are significantly greater than in the representatives of the ecto-mesomorphic somatotype. It has also been found that almost half of the amplitude and derivative indices are significantly higher in girls than in boys of corresponding somatotypes, and most of the time - on the contrary, in boys, than in girls of corresponding somatotypes. Thus, indicators of crus rheogram in practically healthy girls and boys of different somatotypes, inhabitants of the Podillia region of Ukraine have pronounced differences mainly between the representatives of mesomorphic and ectomorphic somatotypes. Established pronounced manifestations of sexual dimorphism of indicators of crus rheogram between adolescents of corresponding somatotypes.

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