ObjectiveIncreases in atonic postpartum haemorrhage (PPH) have been reported from several countries in recent years. We attempted to determine the potential cause of the increase in atonic and severe atonic PPH.DesignPopulation-based retrospective cohort study.SettingBritish Columbia, Canada, 2001–2009.PopulationAll women with live births or stillbirths.MethodsDetailed clinical information was obtained for 371 193 women from the British Columbia Perinatal Data Registry. Outcomes of interest were atonic PPH and severe atonic PPH (atonic PPH with blood transfusion ≥1 unit; atonic PPH with blood transfusion ≥3 units or procedures to control bleeding), whereas determinants studied included maternal characteristics (e.g. age, parity, and body mass index) and obstetrics practice factors (e.g. labour induction, augmentation, and caesarean delivery). Year-specific unadjusted and adjusted odds ratios for the outcomes were compared using logistic regression.Main outcome measuresAtonic PPH and severe atonic PPH.ResultsAtonic PPH increased from 4.8% in 2001 to 6.3% in 2009, atonic PPH with blood transfusion ≥1 unit increased from 16.6 in 2001 to 25.5 per 10 000 deliveries in 2009, and atonic PPH with blood transfusion ≥3 units or procedures to control bleeding increased from 11.9 to 17.6 per 10 000 deliveries. The crude 34% (95% CI 26–42%) increase in atonic PPH between 2001 and 2009 remained unchanged (42% increase, 95% CI 34–51%) after adjustment for determinants of PPH. Similarly, adjustment did not explain the increase in severe atonic PPH.ConclusionsChanges in maternal characteristics and obstetric practice do not explain the recent increase in atonic and severe atonic PPH.
Objective To evaluate the risks and benefits of routine labour induction at 41 +0 weeks' gestation for mother and newborn.Design Population-based retrospective cohort study of interinstitutional variation in labour induction practices for women at or beyond 41 +0 weeks' gestation. Conclusions Within the current range of clinical practice, there was no evidence that differential use of routine induction at 41 +0 weeks affected maternal or neonatal health outcomes.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.