Two Ni-and Cu-free bulk metallic glasses (BMGs) of Zr 65 Pd 17:5 Fe 10 Al 7:5 and Zr 65 Pd 12:5 Ag 5 Fe 10 Al 7:5 , with a critical casting diameter of 6 mm and a compressive strength above 1500 MPa, were developed. While the Zr 65 Pd 17:5 Fe 10 Al 7:5 alloy showed little plastic strain before fracture, the Zr 65 Pd 12:5 Ag 5 Fe 10 Al 7:5 alloy exhibited much larger plasticity by the relatively stable, intermittent propagation of the major shear band under compression. This unusual plastic deformation behavior was interpreted on the basis of the contribution of the icosahedral shortrange order. Potentiodynamic polarization tests revealed that the Zr 65 Pd 12:5 Ag 5 Fe 10 Al 7:5 alloy has a higher corrosion resistance than the Zr 65 Pd 17:5 Fe 10 Al 7:5 alloy in phosphate buffered saline at 37 C. X-ray photoelectron spectroscopy analysis revealed that the passive film of Zr 65 Pd 12:5 Ag 5 Fe 10 Al 7:5 alloy consisted mostly of ZrO 2 , which may be responsible for the excellent corrosion resistance of this alloy. Ni-and Cufree BMGs with a critical diameter of 6 mm, together with enhanced mechanical properties and corrosion resistance, may be promising in biomedical applications.