Background. Stroke is the second-leading global cause of death behind heart disease, accounting for 11.8 % of total deaths worldwide. However, currently, there are not enough published prospective hospital-based cohort studies that report and analyze outcomes of thalamic stroke. The purpose of this study is to determine the features of acute thalamic stroke outcomes in a prospective hospital-based cohort study, providing a comprehensive clinical and neuroimaging analysis of the treatment results and assessing the outcomes of acute thalamic stroke. Materials and methods. We prospectively recruited 319 acute stroke patients, admitted within 24 hours from the onset of the stroke symptoms to the Neurological Center at an academic hospital (Oleksandrivska Clinical Hospital) in Kyiv, Ukraine. Comprehensive neurological, clinical, laboratory, ultrasound, and neuroimaging examination was performed in all patients. Results. MRI/CT-proven thalamic stroke was diagnosed in 34 (10.6 %) out of 319 persons, forming a study group: 22 patients (average age 61.9 ± 10.2 years) were diagnosed with an acute isolated ischemic thalamus infarction; 12 (average age 59.0 ± 9.6 years)-with an acute thalamic hemorrhage. Specific neurological outcomes of infarctions and hemorrhages in different thalamic territories were analyzed, compared, and described.

Актуальность. В статье проанализированы и описаны патофизиологические особенности и закономерности возникновения неврологических, нейропсихологических и клинических сосудистых синдромов таламических инсультов нижнелатерального сосудистого бассейна. Цель исследования: описать и проанализировать клинико-нейровизуализационные особенности сосудистых синдромов таламических инсультов нижнелатеральной сосудистой территории в проспективном клиническом когортном исследовании. Материалы и методы. Мы провели проспективное клиническое когортное исследование 319 пациентов с острым инсультом, поступивших в неврологический центр Александровской клинической больницы (г. Киев, Украина) в течение первых 24 часов с момента развития инсульта. Все пациенты прошли комплексное клинико-неврологическое, лабораторное, ультразвуковое и нейровизуализационное обследования. Результаты. Среди 319 больных с острым инсультом нейровизуализационно подтвержденный таламический инсульт диагностирован у 34 (10,6 %) пациентов. Из них у 22 человек (средний возраст 61,9 ± 10,2 года) обнаружен острый изолированный инфаркт таламуса, а у 12 (средний возраст 59,0 ± 9,6 года) — острое таламическое кровоизлияние. Проанализированы, сравнены и описаны специфические неврологические особенности клинических сосудистых синдромов острых таламических инсультов нижнелатеральной сосудистой территории.

Background. The article covers pathophysiological features and patterns of the occurrence of neurological, neuropsychological, and clinical vascular syndromes of thalamic strokes in anterior and paramedian vascular territories. The features of neurological clinical picture, topical, and neuroimaging diagnosis of thalamic strokes in anterior and paramedian vascular territories are analyzed and described. We purposed to describe and analyze the clinical and neuroimaging features of vascular syndromes of thalamic strokes in anterior and paramedian vascular territories in a prospective hospital-based cohort study. Materials and methods. We have prospectively recruited 319 acute stroke patients, admitted within 24 hours from the onset of the stroke symptoms to the Neurological Center at an academic hospital (Oleksandrivska Clinical Hospital) in Kyiv, Ukraine. Comprehensive neurological, clinical, laboratory, ultrasound, and neuroimaging examinations were performed to all patients. Results. MRI/CT-proven thalamic stroke was diagnosed in 34 (10.6 %) of 319 patients, forming a study group. Twenty-two of 34 patients (average age 61.9 ± 10.2 years) were diagnosed with an acute isolated ischemic thalamic infarction, and 12 patients (average age 59.0 ± 9.6 years) were diagnosed with an acute thalamic hemorrhage. Conclusions. Specific neurological features of clinical vascular syndromes of acute thalamic strokes in anterior and paramedian vascular territories were analyzed, compared, and described.

Background. The article covers pathophysiological features and patterns of the occurrence of neurological, neuropsychological, and clinical vascular syndromes of the thalamic strokes in posterolateral vascular territories. The features of the neurological clinic, topical, and neuroimaging diagnosis of thalamic strokes in posterolateral vascular territories are analyzed and described in a prospective hospital-based cohort study. We aimed to describe and analyze the clinical and neuroimaging features of vascular syndromes of thalamic strokes in posterolateral vascular territory in a prospective hospital-based cohort study. Materials and methods. We have prospectively recruited 319 acute stroke patients, admitted within 24 hours from the onset of the stroke symptoms to the Neurological Center at an academic hospital (Oleksandrivska Clinical Hospital) in Kyiv, Ukraine. Complex neurological, clinical, laboratory, ultrasound, and neuroimaging examinations were performed to all study patients. Results. MRI/CT-proven thalamic stroke was diagnosed in 34 (10.6 %) out of 319 patients, forming a study group. Twenty-two out of 34 patients (average age 61.9 ± 10.2 years) were diagnosed with an acute isolated ischemic thalamic infarction, and 12 patients (average age 59.0 ± 9.6 years) were diagnosed with an acute thalamic hemorrhage. Specific neurological features of clinical vascular syndromes of acute thalamic strokes in posterolateral vascular territories were analyzed, compared, and described.

Background. The article covers pathophysiological features and patterns of the occurrence of neurological, neuropsychological, and clinical vascular syndromes of thalamic stroke in the central vascular territory. The features of neurological clinical picture, topical, and neuroimaging diagnosis of thalamic stroke in the central vascular territory are analyzed and described in a prospective hospital-based cohort study. The purpose of this study is to determine the features of clinical vascular syndromes of acute thalamic stroke in the lower lateral and adjacent (central, posterolateral) vascular territories in a prospective hospital-based cohort study, providing a comprehensive clinical and neuroimaging analysis. Materials and methods. We have prospectively recruited 319 acute stroke patients, admitted to the Neurological Center at an academic hospital (Oleksandrivska Clinical Hospital) in Kyiv, Ukraine, within 24 hours from the onset of the stroke symptoms. Comprehensive neurological, clinical, laboratory, ultrasound, and neuroimaging examinations were performed to all study patients. Results. MRI-/CT-proven thalamic stroke was diagnosed in 34 (10.6 %) of 319 people, forming a study group. Twenty-two of 34 patients (average age 61.9 ± 10.2 years) were diagnosed with acute isolated ischemic thalamic stroke, and 12 (average age 59.0 ± 9.6 years) had acute thalamic hemorrhage. Conclusions. Specific neurological features of clinical vascular syndromes of acute thalamic stroke in the central vascular territory were analyzed, compared, and described.