On an example of a clinical case in a patient with drug addiction, the reviewed clinical and chest X-ray features of community-acquired pneumonia, the diagnostic algorithms and the differential diagnostics are based on the recommendations of the Ukrainian Association of Pulmonology. The treatment strategy of the patient in the conditions of an ambulatory are described. Community-Acquired pneumonia acquired by intravenous drug use is characterized by a severe course, febrile body temperature, severe specific lung disease. On the example of this clinical case, the importance of express diagnostics of pneumonia at the ambulatory stage wasconfirmed to determine the correct tactics of patient management.

Introduction: No doubt today that atrial fibrillation (AF) is associated with an increased risk of thromboembolic events. Simultaneously we did not find any investigation about the links between general cardiovascular risk (GCVR) and the frequency forms and functional parameters of the heart in patients with AF. The aim:To study the frequency forms and functional indices of the heart in patients with permanent AF in GCVR groups. Materials and methods: 157 patients with permanent AF (99 men and 58 women) aged 64.6 ± 9.7 years were examined. The frequency of ventricular contractions, the duration of the ventricular complex (QRS), the corrected QT interval (QTc), power indices of the spectrum of heart rate variability (HRV) were measured by ECG. Echocardiographic parameters were studied using a SIM 5000 plus medical diagnostic automated echocardiograph. Patients were classified into GCVR groups. Results and conclusions: The existence of relationships of GCVR with frequency forms of AF and functional indicators of the heart was established. In patients of the class I-III GCVR groups, the tachysystolic form of AF prevailed. Its frequency increases with the rise of the GCVR class. In GCVR IV, redistribution of forms of AF occurs in the direction of normosystolic ones. Among the functional parameters of the heart, the left ventricular ejection fraction and the power of the HRV spectra are most closely associated with GCVR.

The aim: To establish diagnostic markers of LADA at the stage of manifestation based on the analysis of clinical and anamnestic data, the results of immunological examination of patients with different types of DM. Materials and methods: Study included 121 patients with LADA (1st (main) group), 60 patients with type 1 DM (2nd group), 81 patients with type 2 DM (3d group). The examination included analysis of complaints, medical history, determination of anthropometric data, studies of the level of antibodies to glutamic acid decarboxylase (GAD ab), cytoplasmic antigen (ICA ab), tyrosine phosphatase (IA-2 ab). Results: Criteria of LADA diagnosis included slow nature of DM course, the average age of the disease onset (45,02±9,96) years, combination of diabetic complaints with gradual weight loss, frequent detection of DM (64,46%) on request, fairly high level of glycemia at diagnosis ((14,12±4,57) mmol/l)), the possibility of ketonuria episodes in a certain amount (23,14%) of cases in the absence of acute ketoacidotic states. The presence of excess body weight and even obesity is not a criterion for excluding LADA. Conclusions: To verify the diagnosis of LADA it is necessary to study of at least two types of antibodies. The most conclusive is the determination of GAD ab and IA-2 ab.