Three-dimensional volumetry of fetal LVs by VOCAL method has good agreement with fetal MRI in fetuses with ventriculomegaly and may be used as an additional tool in patient counseling and prognosis prediction.

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There are large differences in the texture of the cervical stroma and CGA on GSH allowing the objective differentiation of the two areas. The CGA/stroma ratio allows the objective assessment of the absence or presence of the CGA.

with abnormal measurements of the fourth ventricle (intracranial translucency -IT) that provided the morphological support to evaluate the efficiency and specificity of posterior brain parameters. Prospectively we evaluated mean values and repeatability of most efficient and specific considered parameters of the posterior brain complex -brain stem diameter (BS), brain stem to occipital bone distance (BSOB) and BS to BSOB ratio were performed in 112 fetuses in 2D before obtaining 3D volumes, used to measure the parameters by the same examiner twice and by another examiner once. Results: Abnormal IT aspects were found in both OSB cases examined in the first trimester, but also in holoprosencephaly and hydrocephalus fetuses. BS and BSOB ratio were found with higher specificity for OSB detection. In the prospective study mean values increased with crown-rump length (CRL) for IT, BS, BSOB and BS to BSOB ratio decreased; the difference between measurements performed by the same sonographer was < 5% in 91% of the cases and between two sonographers < 5% in 88.4% of the paired 3D ultrasound measurements. Conclusions: Preliminary results show that abnormalities in the posterior brain may offer the possibility of first trimester diagnosis of OSB. IT abnormalities should be followed by careful CNS evaluation because false positive aspects of IT are likely to appear in fetuses with other CNS severe anomalies; BS and BSOB ratio ruled out spine anomaly in these cases. Posterior brain measurements are reproducible and the results obtained by 3D and 2D ultrasound are similar. P01.11Correlation of fetal length and area of corpus callosum by 3D sonography with 2D biometric parameters Department of Obstetrics, São Paulo Federal University (UNIFESP), São Paulo, BrazilObjectives: To correlate of fetal length and area of corpus callosum (CC) by three-dimensional (3D) ultrasonography with two-dimensional (2D) biometric parameters. Methods: This cross-sectional study involved 250 normal pregnancies with gestational age between 20 and 33 weeks. An Accuvix XQ equipment (Medison, Seoul, Korea) with a convex volumetric transducer (3-5 MHz) was used. To assess the CC, a transfrontal plane was obtained using the metopic suture as an acoustic window. Length was obtained by measuring the distance between the proximal and distal extremities of the CC. Area was obtained through manual tracing of the external CC surface. Scatter graphs were created to analyze the correlation between CC length and area and biparietal diameter (BPD), abdominal circumference (AC), head circumference (HC) and femur length (FL), the quality adjustments was realized according to the determination coefficient (R2). Results: There was a strong correlation between CC length and area and BPD, AC, HC and FL, with the best model represented by linear equation (R2 = 0. 84, 0.82, 0.86, 0.83, 0.71, 0.68, 0.72 and 0.69, respectively). Conclusions: The fetal CC length and area using transfrontal view by 3D-ultrasonography showed strong correlation with 2D-biometric parameters bet...

Aim: To evaluate the modified myocardial performance index (Mod-MPI) in foetuses with growth restriction and compare this index with appropriate for gestational age foetuses. Material and methods: A prospective cross-sectional case-control study was conducted involving 76 singleton foetuses between 24 and 34 weeks of gestation divided into three groups (24 appropriate growth foetuses, 30 foetuses with estimated weight between the 3 rd and 10 th percentiles and 22 foetuses with estimated weight < 3 rd percentile, according to the Hadlock table). The Mod-MPI was obtained in the plane of the four chamber view, and the spectral Doppler sample volume was placed in the lateral wall of the aorta, close to the mitral valve. Doppler of umbilical artery was normal in all cases. Analysis of variance (ANOVA) was used to compare the groups and the intra-class correlation coefficient (ICC) was used to assess intra-and inter-observer reproducibility. Results: The mean Mod-MPI in the groups of appropriate for gestational age, estimated weight between the 3 rd and 10 th percentiles, and estimated weight < 3 rd percentile was 0.32 ± 0.05, 0.35 ± 0.05 and 0.36 ± 0.06, respectively; there was no statistical difference between the groups (p = 0.072). There was good intra-and inter-observer reproducibility (ICC = 0.726 and 0.760, respectively). Conclusion: Mod-MPI was not significantly different between foetuses appropriate for gestational age and those with growth restriction. Mod-MPI proved to be a feasible and reproducible technique.