Age-related changes in uterine and ovarian morphology and size were studied in 114 normal premenarcheal girls using a real-time mechanical sector scanner. Reference growth values were obtained for total uterine length, anteroposterior diameters of the corpus and cervix, corpus/cervix ratio, and uterine and ovarian volumes. Up to 7 years of age uterine size was not influenced by age and there was a relative predominance of the cervix over the corpus. Thereafter the uterus underwent a regular increase in size and the corpus gradually became larger than the cervix. Ovarian volume was relatively stable up to 5 years, when regular age-related growth started, associated with an increase in cystic functional changes in the ovary. As uterine and ovarian morphology and size are reliable indicators of the degree of sex-hormone stimulation, real-time ultrasound offers a rapid method of studying normal and abnormal pubertal development in girls.

The prognosis of a consistent group of liver cirrhosis patients with variceal bleeding remains poor. The current treatment is highly effective in controlling variceal bleeding, but mortality is related mainly to the severity of liver failure.

We used a real time mechanical sector scanner to evaluate uterine and ovarian size in a large number of normal premenarcheal girls strictly grouped according to age. In addition, we studied the relation between these parameters and puberty and sex hormone concentrations. Patients and methodsA total of 114 premenarcheal girls, whose ages ranged from 2 years to 13 years 11 months, were studied after informed parental consent had been obtained. They were all suffering from minor, nonendocrinologic, acute pathology. Each

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