By enhancing gaseous uptake from the non-ventilated lung during procedures performed thoracoscopically, the rapid diffusion properties of nitrous oxide would be expected to speed lung collapse and so facilitate surgery. To assess the effect of nitrous oxide on the speed of absorptive lung collapse, a study was conducted using 11 anaesthetised sheep. Speed of collapse was assessed in an indirect manner by recording the time required in a closed-chest situation for the airway pressure distal to a single lung airway occlusion to decrease to - 1.0 kPa. The influence of nitrous oxide was assessed by comparing the time taken for this decrease in airway pressure when the animal was being mechanically ventilated with 50% nitrous oxide in oxygen with the time taken when using 100% oxygen. In all assessments, it was found that the decrease in airway pressure to - 1.0 kPa occurred in a shorter time when nitrous oxide was used. The findings lend support to the hypothesis that during thoracoscopic surgery, mechanical lung ventilation with an oxygen/nitrous oxide mixture will increase the rate of gaseous uptake from the non-ventilated lung and so hasten its absorptive collapse.
At the time one-lung ventilation is initiated, nitrogen from the atmosphere may enter the non-ventilated lung via a double-lumen tube connector that has been left open to air, even momentarily. Ongoing oxygen uptake from the non-ventilated lung raises the partial pressure of nitrogen. This should lead to activation of hypoxic pulmonary vasoconstriction and a reduction in intra-pulmonary shunting. However, in spite of this, some patients still become hypoxaemic. In such cases, it may be advantageous to have excluded nitrogen from the non-ventilated lung by connecting it to an oxygen source at ambient pressure. Ongoing apnoeic oxygenation, while the airways are patent, and as the lung collapses, should delay the onset of arterial desaturation. In this paper we review the theoretical basis for apnoeic oxygenation during one-lung ventilation, and in particular on oxygen uptake by the non-ventilated lung prior to and during its subsequent collapse.
The Shikani Seeing Stylet™ is a recently introduced reusable intubating stylet, produced in adult and paediatric versions. It combines features of a fibreoptic bronchoscope and a lightwand. Inside a malleable stainless steel sheath, the Shikani Seeing Stylet™ has a fibreoptic cable leading to a distal light source and high-resolution lens. In use, the stylet is placed in the lumen of the selected endotracheal tube and the light source enables the stylet to be used as a lightwand, while the fibreoptic capability enables visualization of the laryngeal inlet. It is portable, relatively inexpensive and easy to maintain. This report describes the use of the stylet on eight occasions in seven children, all of whom were assessed preoperatively as being potentially difficult to intubate. Three had been difficult to intubate previously. All were anaesthetized using inhalational anaesthesia. Once an adequate depth of anaesthesia had been achieved, conventional direct laryngoscopy was performed and identified as Grade 3 in six of the patients and Grade 1 in one. Tracheal intubation was then attempted using the Shikani Seeing Stylet™. On six of the eight occasions the attempt was made by different anaesthetists, none of whom had any prior clinical experience with the stylet. There were seven successful intubations and one failure in a patient who could not be intubated by any method. The Shikani Seeing Stylet™ seems a useful device for use in children with difficult airway problems, suspected cervical spine instability or limited mouth-opening.
By enhancing gaseous uptake from the non‐ventilated lung during procedures performed thoracoscopically, the rapid diffusion properties of nitrous oxide would be expected to speed lung collapse and so facilitate surgery. To assess the effect of nitrous oxide on the speed of absorptive lung collapse, a study was conducted using 11 anaesthetised sheep. Speed of collapse was assessed in an indirect manner by recording the time required in a closed‐chest situation for the airway pressure distal to a single lung airway occlusion to decrease to − 1.0 kPa. The influence of nitrous oxide was assessed by comparing the time taken for this decrease in airway pressure when the animal was being mechanically ventilated with 50% nitrous oxide in oxygen with the time taken when using 100% oxygen. In all assessments, it was found that the decrease in airway pressure to − 1.0 kPa occurred in a shorter time when nitrous oxide was used. The findings lend support to the hypothesis that during thoracoscopic surgery, mechanical lung ventilation with an oxygen/nitrous oxide mixture will increase the rate of gaseous uptake from the non‐ventilated lung and so hasten its absorptive collapse.
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