Background: Herniation through foramen of Winslow is a relatively rare group of hernias characterized by protrusion of the abdominal contents into the lesser sac. To our knowledge, this is the youngest and the only reported case related to adolescents in the last five years. Case Presentation: A 15-year-old male patient presented to our emergency department after experiencing 4 hours of acute dull upper abdominal pain. We diagnosed the patient with herniation through foramen of Winslow by computed tomography (CT) and other complementary diagnostic methods. After a 3-trocar laparoscopic procedure, the hernia was successfully repositioned and no bowel resection was required. The patient was discharged on the fourth postoperative day without complications. He was no recurrence six months after operation. Conclusions: Through the review of the literature, it is clear that herniation through foramen of Winslow (HFW) is a more challenging condition to diagnose preoperatively, which can be achieved with the help of complementary diagnostics especially CT. As a category of diseases with a very low postoperative recurrence rate, clinical experience tells us that only three-trocar laparoscopic surgery can successfully return HFW.