Liesegang rings (LRs) are benign and concentric non-cellular lamellar structures, occasionally found in kidney, synovium, conjunctiva, and eyelid. They are uncommon pathological findings which may cause diagnostic dilemmas for pathologists. We report a rare case of a 40-year-old female patient presenting with the left-sided lumbar pain, burning micturition, and hematuria for 1 week. With the radiological impression of a renal tumor, she underwent left radical nephrectomy. A diagnosis of clear cell renal cell carcinoma, the WHO/ISUP Grade II, and a stage of pT2aNxMx was made. An additional feature noted was the presence of LRs at the periphery of the tumor. It is important to recognize these rings to avoid mistaking them with parasites and dystrophic calcification. Hence, awareness among pathologists about these lesions would help in the proper management of the patients.
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