Background: Jaundice is one of the most common problems occuring in the neonatal period. Phototherapy plays a major role in its treatment. However, this treatment modality may itself result in inherent complications which even contributes to the development of convulsions. Hence this study is carried out to evaluate serum calcium levels in full term neonates receiving phototherapy for jaundice. Aim and objective: To determine the effect of phototherapy on serum calcium level in full-term hyperbilirubinemic neonates. Methods: After getting Ethical Committee approval informed, written consent from the mother the medical history, general examination, systemic examination of the neonate was carried out. This study was performed on 30 full-term jaundiced neonates (15 males and 15 females) receiving phototherapy. Laboratory tests including total serum bilirubin measured by Diazo method and serum calcium level measured by Arsenazo III method were carried out before and after 48 hours of phototherapy. Results: Statistical analysis was done using Paired t test. After 48 hours of phototherapy, there was a significant decrease in serum calcium levels from 9.51±0.29 mg/dl to 8.38±0.31mg/dl (p=0.014) in eighteen neonates (60%) . None of the neonates were clinically symptomatic. Conclusion: This study shows a decrease in serum calcium levels in term infants exposed to phototherapy. Hence serum calcium should be monitored regularly for neonates receiving phototherapy.
Background: Female coronary heart disease morbidity rate accelerate after the age of 45years. Altered serum lipid profile seen in menopause is one of the major determinants for developing cardiovascular diseases. Changes in lipid level in relation to the duration of menopause is to be investigated to prevent the emerging cardiovascular diseases. Aim and objective: To study the effect of duration of menopause on serum lipid profile in postmenopausal women. Methods: After getting ethical committee approval, in this cross sectional study, postmenopausal women attending Government Rajaji Hospital for master health checkup were selected. Women with duration of menopause less than 10years (n=30) were taken as group-I and more than 10years (n=30) were taken as group-II and estimation of serum lipid profile was done for all of them. Results: Statistical analysis was done by student's t test and the results were compared between group-I and group-II. In group-II, the mean values of total cholesterol (p=0.006) and low density lipoprotein levels (p<0.001) were increased significantly. However there was a significant decrease in high density lipoprotein level (p< 0.001). Conclusion:The elevated low density lipoprotein and the reduction of high density lipoprotein level increases the risk of developing cardiovascular diseases. So specific health education strategies are needed in postmenopausal women of longer duration.
Infertility is defined as the inability to become pregnant after 12 months of regular, unprotected intercourse. Among couples 15-44 years of age, nearly 7 million attend infertility clinics Chandra et al. Etiology of infertilitycombined factors-40%, male factors-26-30%, ovulatory dysfunction 21-25%, tubal factors-14-20%, uterine, cervical, peritoneal factors-10-13%, unexplained 25-28% Thonnaeu et al.
The metabolic syndrome has received a great deal of attention in the last few decades. Metabolic syndrome is a group of anthropological and biochemical abnormalities that predispose a person to cardiovascular disease, Type 2 Diabetes Mellitus and stroke. It is a group of interrelated abnormalities namely central obesity, raised blood pressure, high triglycerides, decreased levels of high-density lipoprotein (HDL) cholesterol and elevated fasting glucose levels. This is a common metabolic disorder which increases in prevalence as the population becomes more obese. The prevalence of metabolic syndrome in developing countries is also promptly increasing. A study by Misra A and Khurana L in 2008 showed that the situation is similar in India with the recent data suggesting that upto one fourth and one third Indian adult population suffer from metabolic syndrome. It is obvious that occupational drivers are associated with considerable changes in lifestyle habits. The aim of the present study is to evaluate the contribution of stress and duration of years of service on metabolic syndrome among occupational drivers in Madurai district. Ncep:Atpiii 2001-Criteria:-According to it, metabolic syndrome is present if three or more of the following five criteria are met: Blood pressure: systolic ≥ 130 or diastolic ≥ 85 mmHg. Fasting triglyceride (TG) level : Triglycerides ≥150mg/dl. Waist circumference :>40 inches (male), >35 inches (female) Fasting plasma glucose: ≥ 110mg/dl. Fasting HDL level: <50 mg/dl (male), < 40 mg/dl (female) Modified ncep atpiii-criteria for the metabolic Syndrome:-In 2005, the American Heart Association and the National Heart, Lung and Blood Institute (AHA / NHLBI) conducted a revision of the metabolic syndrome diagnostic criteria-modified NCEP ATPIII criteria. The important changes in the modified AHA/NHLBI definition, ATPIII
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