Background. To study the features of the structure and spectrum of etiological allergens in allergic diseases in a changing climate taking into account the climatic characteristics the analysis of medical documentation and allergological examination of the Moscow region patients. Methods. The number of patient’s visits in the clinical department of the Institute of immunology, Moscow, Russia, for the fiveyear period (2008 to 2012) as well as the pollen monitoring data during the seasonal period from 2008 to 2012 were estimated. Results and conclusion. It was found that the debut of bronchial asthma in patients with pollinosis directly depends on a high pollen concentration in the atmospheric air (above 20 000 pollen grains per m3 of air). The influence of climatic and weather conditions on the formation, aggravation and severity of allergic diseases in the case of patients living in the Moscow region have been established.

The paper presents a variety of skin symptoms of allergy to insects bites, clinical and laboratory criteria for the early detection of this type of allergy, the main approaches of treatment and prevention.

The revised recomendations on chronic urticaria diagnostics and treatment created by leading Russian experts are presented.

The updated Federal clinical recommendations on urticaria are presented (2018).

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