GSK3β and p-GSK3β (Ser 9) can be observed and may be involved in alveolar bone resorption and inflammatory response in periapical lesions, as well as associated with periapical lesion pathogenesis.

CX3CL1 and CX3CR1 are related to the development of periapical lesions. The chemokine and its receptor may be involved in the progression of tissue destruction, including bone resorption, during periapical inflammation.

The settlement and vernacular architecture in Yunnan can be imagined as a living organism which is the outcome of centuries of optimization of topography adaption, climate consideration, material use, construction techniques, etc. The environment and the multiple forms of Yunnan traditional dwellings reflect the balanced development of residential houses, cultural background and natural ecology, forming regional context and system. This paper aims to explore and evaluate sustainable vernacular architecture and settlement from a settlement layout, architecture form and natural architecture materials so as to put forward the sustainable perspective. It also can be taken as an example for modern building and landscaping design.

These findings suggest that CCRT with low-dose docetaxel inhibits the growth of DU-145 prostate cancer xenografts, by enhancing apoptosis and suppressing angiogenesis. Based on these preclinical findings, we suggest that CCRT for the treatment of prostate cancer deserves further development.