Forty-one of the 44,255 road accidents reported to the police in one region of Sweden during 1959-63 were, or probably were, caused by sudden illness in the driver of a motor-vehicle. All 4I were males. The illness was most often due to epilepsy or myocardial infarction. Eight drivers died at the wheel from their disease. No other persons were killed in the 4I accidents. Only in I9 out of the 4I cases was there any possibility of a previous medical examination having indicated that the man was unfit to drive. In view of this, and the extremely small proportion-about I in i,ooo-of accidents caused by sudden illness at the wheel, there is little point in providing for general measures such as periodic medical examination to prevent these accidents. Attention should be directed to other types of accidents and other groups of drivers.

Because of the great interindividual differences in tumour aggressiveness within the family it is impossible to predict whether an individual gene carrier will have an aggressive MTC or not. This unpredictability is an additional argument, besides those obtained in stratified genetic studies, for operating on gene carriers at young age.

Six hundred and twelve drivers with chronic disease, mainly diabetes, cardiovascular disease, renal disorders, and diseases of the sense organs, were investigated with regard to the frequency of road accidents and serious driving offences during a Io-year period. Road accidents directly caused by the disease or its treatment occurred in four (o-8%) cases, all due to hypoglycaemic attacks in insulin-treated diabetics. A comparison was made between the investigation series and a control series identical with regard to number, sex, age, and duration of licence-holding. About 50% of the drivers in each series were asked about their exposure to traffic; this proved to be similar in both series. The percentages of drivers experiencing road accidents were 4-I in the investigation series and 7-7 in the control series. The corresponding figures for road accidents and serious driving offences taken together were 9-8% and I5.3%. The con-

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