This case report describes the orthodontic treatment used to prepare for restorative dentistry, aimed at the functional rehabilitation of an adult patient with Class I malocclusion, right posterior crossbite, and significant tooth wear on the palatal face of the maxillary canine to canine. The orthodontic treatment was performed with a total fixed appliance mini-expandex-type expander, associated with vertical elastics. Good dental intercuspation was obtained and enabled conditions for the restoration of the abrasions on the palatal surfaces of the maxillary incisors and canines and the tips of the buccal cusps of the maxillary right premolars and first molar. Excellent results were found during a 37-month follow-up.
Objective
To investigate the association of genetic polymorphisms (tagSNPs type) of RANK/RANKL/OPG genes with the loss of orthodontic mini‐implants (MIs).
Setting and sample population
One hundred and thirty‐five patients of both sexes, with mean age of 48.7 ± 10 (20‐76 years), were studied. The control group was composed of 104 patients, with no MI lost and functioning for at least 6 months and the case group, of 31 patients with at least one MI lost.
Materials and methods
Cells were obtained by mouthwash with 3% glucose solution for 1 minute and scraping the buccal mucosa with sterilized spatula. DNA was extracted from buccal epithelial cells with 10 M ammonium acetate and 1 mM EDTA. Genotyping was performed by the real‐time polymerase chain reaction (PCR) technique. Univariate and multivariate analyses were performed (P < .05).
Results
No markers were associated with MI loss after Benjamini and Hochberg false discovery rate correction of Univariate tests. In the multivariate analysis, the variables that associated with MI loss were the number of MIs installed (P < .000) and the polymorphism rs8086340 in the RANK gene (P = .018).
Conclusion
A higher number of MIs installed (P < .000) and polymorphism rs8086340 in the RANK gene (P = .018) were associated with loss of orthodontic MIs after multivariate analysis.
There has been a progressive increase in demand for orthodontic treatment for adult patients. A 40-year-old female came to the orthodontic clinic complaining of overcrowding and midline deviation. Clinical examination showed facial asymmetry and midline deviation due to the extraction of the maxillary and mandibular first premolars of the right side. A periapical radiograph showed a severe root resorption in the maxillary central and lateral incisors. The treatment objectives were to correct the midline deviation, close the open bite, correct the bilateral posterior crossbite, and obtain a Class I relationship for the molars and canines on both sides. This case report shows a treatment approach that was effective in correcting all problems of malocclusion that the adult patient presented. The treatment results have established a new functional and stable occlusion with improvement of facial esthetics, and the roots were no shorter than before treatment.
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