Background: Acute pancreatitis (AP) is as an inflammation of the pancreas with varied range of complication like peri-pancreatic collection, pancreatic necrosis, renal failure, multi-organ dysfunction syndrome which increases mortality rate and morbidity. Majority of AP cases are mild but severe cases of AP are associated with increased complication and mortality. BISAP is simple bedside prognostic scoring system for predicting severity of AP. BISAP is a collection of simple routine investigation and scores are quantified at 24hours of onset of AP. This study aims to assess prognosis of AP cases at ESIC Medical college and Post Graduate Institute of Medical Science and Research, Bangalore, Karnataka, India.Methods: A prospective study of 60 Patients who were diagnosed as AP according to RAC. All patients were admitted in high dependency unit with close observation of vital parameters and investigations were done at 24 hours of onset of AP. BISAP score >3 was considered as Severe Acute Pancreatitis, its correlation with local complications, organ failure, ICU stay and Mortality was studied. Statistical analysis done using Chi-square test and Fisher Exact test for local complications and organ failure using xL Stat and SPSS v.21.0, a p-value <0.05 was considered to be significant.Results: Of the 60 patients, BISAP score was >3 and <3 in 15 and 45 patients respectively. Alcohol was the most common cause of acute pancreatitis, accounting for 53.33%. In current study 12 (20%) patients developed organ failure and among them 9 (75%) had transient organ failure and 3 (25%) had persistent organ failure. Total 8 (13%) patients had developed pancreatic necrosis and among them 6 had BISAP >3. Mortality rate in this study was 2%.Conclusions: The BISAP score is a simple and fairly accurate method for the early identification of patients at increased risk for in hospital mortality and to identify patients at risk of the development of intermediate markers of severity and organ failure within 24 hours of presentation.

AIMS AND OBJECTIVESTo determine the prognostic factor for mortality and to review our experience on the various surgical methods in the management of typhoid ileal perforation.

Introduction:Androgen insensitivity syndrome is a form of male pseudohermaphrodite where the phenotype female has male gonads and is genotypically male.Case report: We report a case of complete androgen insensitivity syndrome in a 22-year-old who underwent laparoscopic gonadectomy.Discussion: Androgen insensitivity syndrome is the most common cause of male pseudohermaphroditism and third most common cause of primary amenorrhea. Conclusion:Laparoscopy is an effective method in androgen insensitivity syndrome treatment, mainly due to the increased risk of malignant transformation of the testes. Psychosexual needs should be addressed along with low-dose hormonal therapy to maximize long-term success.

Introduction: Modern therapy for the breast cancer has evolved to include both surgical and systemic therapy. The Modified Radical Mastectomy (MRM) is the standard treatment option for most of the patients with breast cancer. Early complications are defined here as complications occurring within 30 days after surgery. The initial complications following MRM includes wound infections, seromas, chronic pain, flap necrosis and haematomas. Aim: To study the frequency of occurrence of outcomes such as, seroma, haematoma, flap necrosis, Surgical Site Infection (SSI) following MRM and to associate the outcomes with the clinical, demographic, intraoperative and postoperative factors. Materials and Methods: The present study was a single centre longitudinal cohort study with sample size of 72. Patients who are admitted for MRM for carcinoma breast between January 2019 to January 2020 in Department of General Surgery, ESIC MC & PGIMSR, Rajajinagar, Bengaluru, Karnataka, India, were taken for study after considering the inclusion and exclusion criteria. The data of risk factors collected were entered into a proforma. After surgery they were observed postoperatively for early complications. They were followed-up for a period of one month. Information was entered in Statistical Package for the Social Sciences (SPSS) software. Descriptive statistics comprising of mean, average, standard deviation, proportion, and percentage were used. Comparison of continuous data was done by Student's t-test and categorical variables were compared using Chi-square test. Variables with p-value <0.05 were considered as significant risk factor. Results: Out of the 72 patients, who underwent MRM 27 (37.5%) developed seroma, 6 patients (8.3%) developed SSI and 9 patients (12.5%) developed flap necrosis. There was significant association between Seroma Formation (SF) and higher age (p=0.026), higher BMI (p=0.001), hypertension (p=0.004) and drain volume on day 1 (p<0.001). There was significant association between SSI and Diabetes Mellitus (DM) (p=0.002), prolonged duration of drain (p=0.03). There was significant association between flap necrosis and DM (p=0.003). Conclusion: The incidence of seroma was higher in older, hypertensive and in more obese patients. It was decreased was decreased by flap fixation under muscles. The incidence of SSI and flap necrosis was higher among diabetic patients. Optimisation of glycaemia will help in reducing both.

Background: Although traditional surgery is the gold standard treatment for hemorrhoids, stapled hemorrhoidopexy (SH) is an alternative surgical technique. However, this technique has concerns of recurrence. We conducted this study to assess the clinical outcomes and complications of SH in patients visiting our institution Methods: A prospective study was conducted on 115 patients from 2010 to 2012 who underwent SH with PPH03 kit under spinal anesthesia. Clinical outcomes assessed included the operation time, hospital stay and rate of post-operative pain. Results: SH had lower operative procedural time (30 minutes), post-operative pain and hospital stay (1.8 days) along with minimal procedural complications and were comparable to the previous reports. Conclusions: Stapled hemorrhoidopexy is an effective alternative to traditional surgical technique in treating 3rd and 4th degree hemorrhoids, in terms of lesser operative procedural time, post-operative pain, use of analgesics and hospital stay along with reduced procedure related complication.