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The current study was designed to investigate the drinking patterns and association between socio-demographic factors and adolescents’ alcohol use among high school students from China’s three metropolises, Beijing, Shanghai, and Guangzhou. Using a self-administered questionnaire, we conducted a cross-sectional survey among 13,811 high school students from 136 schools between May and June 2013. A two-stage stratified sampling method was used for subject selection. The prevalence of lifetime drinking was 52.5%; in addition, 38.5% of the students were past-year drinkers, while 20.1% of them had consumed alcohol in the past 30 days. During the past year, 29.7% of the students reported that they drank once per month or less, and 22.0% of the students drank less than one standard drink (SD) per occasion. For the students who were not living with their mothers, as well as the students in higher socioeconomic status (SES), the adjusted odds of past and current drinking were significantly higher, compared with those who lived with both parents and low SES. Due to the high prevalence of alcohol consumption among junior and senior high school students in metropolises, attention should be paid by parents, school administrators, educational and public health agencies for making efforts collectively to reduce alcohol availability and drinking among adolescents.

The objective of the study was to assess the associations of dyslipidaemia, combined oral contraceptive (COC) use and their interaction on the risk of hypertension in Chinese women. In a case-control study, we evaluated 665 hypertensive women and 665 normotensive women matched on region and age in China. Hypertensive women had a higher prevalence of dyslipidaemia and higher levels of total cholesterol, triglyceride, low-density lipoprotein-cholesterol and lipoprotein a than normotensive ones (Po0.05). The risk of hypertension gradually increased with the increasing cumulative time of COC use in women (P ¼ 0.0043), especially significantly increased among those with cumulative time of COC use15-20 and X20 years (adjusted odds ratio (OR) ¼ 1.46, 95% confidence interval (CI): 1.00-2.15; OR ¼ 1.49, 95% CI: 1.06-2.11), but gradually decreased from stopping use of COC (Po0.0001). The multiplicative interaction between dyslipidaemia and accumulative time of COC use X15 years, dyslipidaemia and family history of hypertension, or family history of hypertension and accumulative time of COC use X15 years was confirmed and the interaction analyses showed that they can significantly increased the risk of hypertension (adjusted OR ¼ 2.82, 95% CI: 1.59-3.27; OR ¼ 4.33, 95% CI: 3.10-6.06; OR ¼ 4.56, 95% CI: 3.07-6.77). It is concluded that dyslipidaemia, accumulative time of COC use X15 years and their interaction increased the risk of hypertension.