Articles you may be interested inUltrasensitive near-infrared cavity ring-down spectrometer for precise line profile measurement Rev. Sci. Instrum. 81, 043105 (2010); 10.1063/1.3385675 Design and performance of a wide-bandwidth and sensitive instrument for near-infrared spectroscopic measurements on human tissue Rev. Sci. Instrum. 75, 5315 (2004); 10.1063/1.1818588 High Pressure FTIR/Raman Studies on Molecular Conformation of Proteins and Model Peptides AIP Conf. Quantitative analysis of corroded copper patina by step scan and rapid scan photoacoustic Fourier transform infrared spectroscopy Rev. Sci. Instrum. 74, 331 (2003); 10.1063/1.1517740 Quantitative diode laser absorption spectroscopy near 2 μm with high precision measurements of CO 2 concentration Rev. Sci. Instrum. 72, 4228 (2001);We present the use of a near-infrared ͑IR͒ laser Raman spectroscopy instrument to measure the concentrations of many important analytes at their clinically relevant levels in the simulated human serum. The Raman signal is generated by a 745 nm diode laser in a disposable waveguide capillary cell that contains a submicroliter sample. The Raman spectrum is acquired from the sample in 10 s. The major error in quantitative Raman spectroscopy caused by the variation in laser power, optical alignment, and capillary cell size from measurement to measurement is eliminated by normalizing the spectrum to the dominant water peak at 3350 cm Ϫ1 . Concentrations of glucose, acetaminophen, albumin, and other analytes are predicted using partial least squares ͑PLS͒ calibration. An effective multiple bandpass-filtering method was developed to enhance the signal of the desired analytes to interfering background ratio for improvement of PLS calibration accuracy. It is demonstrated that the accuracy of predicted concentrations for all analytes in the simulated human serum samples are highly acceptable for clinical diagnosis. The results promise the potential applications of the near-IR Raman instrument in medical practice.

On the basis of signed-digit negabinary representation, parallel two-step addition and one-step subtraction can be performed for arbitrary-length negabinary operands. The arithmetic is realized by signed logic operations and optically implemented by spatial encoding and decoding techniques. The proposed algorithm and optical system are simple, reliable, and practicable, and they have the property of parallel processing of two-dimensional data. This leads to an efficient design for the optical arithmetic and logic unit.

Based on a negative binary number system, an algorithm with weighted-shifted addition, parallel-array multiplication, and a two-stage-array complex operation is proposed to carry out the multiplication of two complex numbers. The complex multiplication is performed without signs, carries, and recoding. The algorithm is suitable for optical implementation, and an optical parallel architecture is suggested. The experimental result is also given.

An ordered gray-scale erosion is suggested according to the definition of hit-miss transform. Instead of using three operations, two images, and two structuring elements, the developed operation requires only one operation and one structuring element, but with three grayscale levels. Therefore, a union of the ordered gray-scale erosions with different structuring elements can constitute a simple image algebra to program any combined image processing function. An optical parallel ordered gray-scale erosion processor is developed based on the incoherent correlation in a single channel. Experimental results are also given for an edge detection and a pattern recognition. © 1998 Society of Photo-Optical Instrumentation Engineers. [S0091-3286(98)