Coexistence of the skin manifestations of systemic sclerosis and psoriasis is rare. The link between systemic sclerosis and psoriasis has been poorly investigated. We report a case of a 70‐year‐old woman, who was diagnosed with diffuse cutaneous systemic sclerosis and psoriasis vulgaris and was treated with oral azathioprine (50 mg/d) and prednisolone (10 mg/d), topical corticosteroids, and calcipotriols. The erythema and plaques almost disappeared after 1 week, and the symptoms of discoloration in cold, regurgitation, and dysphagia abated after 3 months.
BackgroundSuperficial lymphatic malformation (SLM) is a congenital disorder of the lymphatic channels. It usually appears as clusters of vesicles filled with lymphatic fluid and blood on the skin that resemble frogspawn, making it difficult to distinguish from haemangiomas, angiokeratomas, and pyogenic granulomas. Although pathological results have diagnostic values, the significance of noninvasive examination in the diagnosis and differential diagnosis is also worth exploring.Materials and MethodsA 24‐year‐old female presented with a history of multiple asymptomatic, pink lesions located on the chest since age 10. Histopathological examination was performed, and results informed the diagnosis of SLM. Lesions were detected by dermoscopy and reflectance confocal microscopy (RCM).ResultsDermoscopy (polarized, 30×) revealed multiple yellowish‐red lacunae in a light red background that were separated by pale septa and “hypopyon sign” was observed. RCM displayed a honeycomb pattern and multiple dark cavities in the upper dermal layers separated by thin septa with a few hypo‐refractile cells at the periphery that demonstrated slow fluid flow via dynamic scanning.ConclusionWe described a case of SLM detected by dermoscopy and RCM. Dermoscopic and RCM features may provide a potentially powerful, noninvasive instrument for the recognition and differentiation of SLM.
Sebaceous gland hyperplasia (SGH) is a benign cutaneous proliferation of the sebaceous glands that occurs in approximately 1% of the healthy population, mainly males. Our aim was to describe dermoscopy and reflectance confocal microscopy features of sebaceous gland hyperplasia. Thirty-one patients with sebaceous gland hyperplasia diagnosed according to the clinical and histopathological standards were examined using dermoscopy and reflectance confocal microscopy (RCM) from March 2018 to January 2022. Dermoscopically, lesions revealed yellowish-red background and faintyellow background in 25 cases (80.65%) and 6 cases (19.35%) respectively. White-yellowish lobulated structures in the center of the lesion were presented in 31 cases (100%) and umbilications in 19 patients (61.29%). Crown vessels in the peripheral of the lesions were observed in 11 cases (35.48%) while irregular linear vessels on the surface of the lesions in 18 cases (58.06%). Under the reflectance confocal microscopy, all lesions presented a honeycombed pattern in the epidermis and typical morulae-shaped sebaceous lobules in dermis. Dilated follicular infundibulum was observed in 15cases (48.39%) and dilated vessels in 26 cases (83.87%). In conclusion, dermoscopy and RCM enable us to describe the imaging features of SGH. Combing the two useful tools together provides a non-invasive basis for the accuracy of clinical diagnosis.
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