The discussion is based on "enthusiastic reception, patient speaking, careful observation, sincere help, warm heart, loving visit" (hereinafter referred to as "six hearts") Objective: To explore the practical effect of "six hearts" nursing service process on improving nursing students' humanistic quality. Methods: Taking nursing undergraduates from a medical college in 2016 and 2017 as the research object, 82 nursing undergraduates in 2016 were set as the control group, clinical nursing teaching was carried out by traditional teaching methods, and 84 nursing undergraduates in 2017 were set as the observation group. The "six -heart" nursing service process education was added to the traditional teaching methods, and the humanistic quality scores of the two groups of nursing students were compared. Results: the scores of humanistic accomplishment in the observation group were significantly higher than those in the control group (all p & lt; 0.01). Conclusion: The "six hearts" nursing service flow runs through clinical nursing students' teaching, which is conducive to improving nursing students' clinical communication ability and humanistic quality, laying a good foundation for reserving excellent nursing professionals and ensuring nursing quality while improving the teaching level of nurses.