The article is devoted to the problem of theoretical consideration of the best neuropsychological technologies for maintaining, strengthening and developing the occupational health of a specialist, particularly from the risk group of occupational diseases, nervous exhaustion, stress, neurosis and emotional burnout. Important criteria of occupational (psychological) health are considered. The concept of occupational health in the neuropsychological context is clarified. The criteria of occupational health and scientific approaches to consideration of neuropsychological technologies of occupational health development by foreign and domestic researchers are generalized. Occupational well-being is identified as the main criterion of occupational health. The role of neuropsychological prevention of burnout is indicated. Neuropsychological recommendations have been developed to ensure and maintain occupational health of specialists in the process of their professional development, in particular in the professional system “human – human”. Neuropsychological factors of occupational health are specified. It is noted that the state of occupational health may be associated with functional asymmetry of the brain, which requires development and implementation of neuropsychological programs to restore occupational health of professionals from a risk group.