Goal.  Find out the cause of unsatisfactory treatment outcomes in patients with destructive forms of erysipelas in the general population. Materials and methods. Retrospectively and prospectively analyzed 284 case histories of patients who were hospitalized in the center of purulent - septic surgery KNP "City Hospital G3" Zaporozhye for the period 2016-2022. Results. It was found that most often the local focus was localized on the upper and lower extremities. The most common clinical manifestations of intoxication in bullous and phlegmonous forms of erysipelas were: general weakness, hyperthermia, muscle pain. In the necrotic form of erysipelas, patients showed signs of severe intoxication with nausea, vomiting and confusion. In the complex treatment of patients with erysipelas, the main place belongs to the early surgical treatment of the area of ​​the pathological process and antibiotic therapy (ABT). Determination of serum procalcitonin allows to assess the progression and generalization of the process and is a sensitive test for the effectiveness of treatment. Conclusions. Radical surgery and timely targeted ABT are key elements of success in the treatment of surgical forms of erysipelas and are not subject to revision. The main causes of unsatisfactory consequences in patients with erysipelas are: aggravation of the disease at the time of hospitalization by septic shock and multiple organ failure, severe decompensated comorbidities. Procalcitonin is a diagnostic marker that can predict the development of sepsis. Key words: erysipelas, unsatisfactory treatment consequences, procalcitonin.