Coumarins are the most important oxygenated heterocyclic of natural compounds. They are widely used as raw materials in many areas such as agrochemical, perfume, pharmaceutical industries. They therefore have several physical, chemical and biological properties. In order to enlarge this family of compounds and elucidate almost all of its properties, researchers have developed various synthetic methods that are not very complex and less expensive. Thus, from 4-hydroxycoumarin we have synthesized a series of 3-acyl-4-hydroxycoumarins by C-acylation. This study is therefore dedicated to the reactivity of 3-acyl-4-hydroxycoumarins. The synthesized coumarins showed a high reaction potential based on the chemical functions present in their structures. To enhance them later, we can try to graft other functions which can be the subject of several transformations such as: condensation, functionalization, cyclization, acylation. So to access more interesting new poly-functionalized compounds both at the reactivity and biological level. These molecules (3-acyl-4-hydroxycoumarins) being new, very little information is known on their physicochemical behavior in writings. On the other hand, the reactivity of molecules with similar structures to those of acyl-hydroxycoumarins such as 4-acylisochroman-1,3-diones and 3-acetyl-4-hydroxycoumarin have been the subject of scientists' work. It emerges from this study that 3-acyl-4-hydroxycoumarins shows strong chemical reactivity which can be used biologically.

This article reports a strategy to synthesize a hybrid species made of iron phthalocyanine (FePc) grafted to the surface of silver nanoparticles. The affinity between sulfur and silver on the one hand, and the aptitude of the FePc complex to bind pyridine axially on the other, allowed us to use thiopyridine as a linker between the two entities. The hybrid species, isolated in the solid form for the first time, has been characterized by optical and vibrational spectroscopy, and by transmission electron microscopy. These studies confirm the good aptitude of the linker to connect the FePc to the silver nanoparticles.