Urban heat island (UHI) effects can strengthen heat waves and air pollution episodes. In this study, the dampening impact of urban trees on the UHI during an extreme heat wave in the Washington, D.C., and Baltimore, Maryland, metropolitan area is examined by incorporating trees, soil, and grass into the coupled Weather Research and Forecasting model and an urban canopy model (WRF-UCM). By parameterizing the effects of these natural surfaces alongside roadways and buildings, the modified WRF-UCM is used to investigate how urban trees, soil, and grass dampen the UHI. The modified model was run with 50% tree cover over urban roads and a 10% decrease in the width of urban streets to make space for soil and grass alongside the roads and buildings. Results show that, averaged over all urban areas, the added vegetation decreases surface air temperature in urban street canyons by 4.1 K and road-surface and building-wall temperatures by 15.4 and 8.9 K, respectively, as a result of tree shading and evapotranspiration. These temperature changes propagate downwind and alter the temperature gradient associated with the Chesapeake Bay breeze and, therefore, alter the strength of the bay breeze. The impact of building height on the UHI shows that decreasing commercial building heights by 8 m and residential building heights by 2.5 m results in up to 0.4-K higher daytime surface and near-surface air temperatures because of less building shading and up to 1.2-K lower nighttime temperatures because of less longwave radiative trapping in urban street canyons.

Background : We have reported that doxycycline-induced over-expression of wild type prion protein (PrP) in skeletal muscles of Tg(HQK) mice is sufficient to cause a primary myopathy with no signs of peripheral neuropathy. The preferential accumulation of the truncated PrP C1 fragment was closely correlated with these myopathic changes. In this study we use gene expression profiling to explore the temporal program of molecular changes underlying the PrP-mediated myopathy.

The COVID-19 pandemic devastated public welfare worldwide, bringing excess deaths connected to causes such as homicide, substance abuse, and heart disease. In the U.S., these mortality increases disproportionally impacted communities of color and contributed to a rise in bereavement among adults and children. The death of an important person is one of the most frequently reported disruptive childhood experiences. According to 2023 Childhood Bereavement Estimation Model (CBEM) results, one in 14 U.S. children will experience the death of a parent by age 18. The current study analyzes the impact of the pandemic on childhood bereavement due to parent death by comparing CBEM results for 2021 and 2020 to the average of annual results for 2016 through 2019 for combined U.S. Census race and Hispanic origin categories. Analyses demonstrate that more than 700,000 U.S. children were newly bereaved due to a parent's death in 2020 and 2021. 2020 increases were observed for each race and Hispanic origin population, ranging from 14.9% to 72.4% compared to the 2016–2019 annual average. Hispanic Asian Pacific Islander and Hispanic Black youth experienced the largest percentage increases, while non-Hispanic white youth experienced the smallest. The results contribute to the growing evidence documenting longstanding and enduring disparities in critical U.S. health outcomes based on race and Hispanic origin. Recommendations for the scale and focus of efforts to understand and address bereavement in a way that accommodates the rising need for support in diverse populations to help all bereaved children find hope and healing are offered.

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