Extracellular matrix grafts may be a viable alternative to other biomaterials for corneal grafting in equids. Advantages include commercial availability and shelf storage.

Objective To evaluate the postoperative effect of intracameral tPA (alteplase; Activase®, Genentech, San Francisco, CA), administered at immediate conclusion of phacoemulsification, on anterior chamber fibrin formation in dogs. Procedures Forty‐one dogs (82 eyes) undergoing bilateral phacoemulsification received 25 μg/0.1 mL intracameral tPA in one eye and 0.1 mL unmedicated aqueous vehicle in the contralateral eye immediately after corneal incision closure. Intraocular pressure (IOP) was measured, and severity of anterior chamber fibrin formation, aqueous flare, pigment precipitates on the intraocular lens (IOL) implant, posterior capsular opacification (PCO), and corneal edema were graded at approximately 1 week, 2‐3 weeks, 4‐6 weeks, 8‐12 weeks, and greater than 3 months postoperatively. Results Anterior chamber fibrin developed postoperatively in 68.3% of dogs (28/41) and 50% of eyes (41/82). In tPA‐treated eyes, 53.7% (22/41) developed fibrin compared to 46.3% of control eyes (19/41). Some degree of postoperative ocular hypertension (POH) occurred in 53.7% of dogs (22/41) and 36.5% of eyes (30/82). In tPA‐treated eyes, 34.1% (14/41) experienced POH compared to 39% of control eyes (16/41). Additional intracameral tPA injection was later required in 29.3% of both tPA‐treated (12/41) and control eyes (12/41). Conclusions Administration of intracameral tPA at immediate conclusion of canine phacoemulsification had no clinically observable effect on anterior chamber fibrin incidence at any time point. tPA‐treated eyes showed no prophylaxis against POH or secondary glaucoma compared to control eyes and received late postoperative tPA injections at the same frequency as control eyes.

Objective To report intraoperative findings and complications associated with cataract surgery performed after retinal reattachment surgery (RR) via pars plana vitrectomy (PPV) using perfluoro‐n‐octane (PFO), laser retinopexy, and silicone oil tamponade in dogs. Animals Studied Retrospective record review of dogs that underwent post‐RR cataract surgery. Signalment, time between RR and cataract surgery, type of lens extraction, postoperative visual status, and intra‐ and postoperative complications were recorded. Cataract formation or progression after RR was categorized as early (≤12 months) or late (>12 months). Results A total of 36 dogs (41 eyes) were included. Average time between RR and cataract surgery was 665 days (median: 546). Early postoperative incidence of cataracts occurred in 19 eyes (46.3%). Types of lens extraction included phacoemulsification with intraocular lens (86.1%, 31/36 dogs), phacoemulsification alone (11.1%, 4/36 dogs), and intracapsular lens extraction (2.8%, 1/36 dogs). Visual improvement occurred in 95.1% of eyes (39/41) immediately postoperatively. Long term, 93.9% of eyes (31/33) maintained vision at 1 month, 85.2% of eyes (23/27) at 3 months, 77.3% of eyes (17/22) at 6 months, and 60% (12/20) at 12 months postoperatively. The most common postoperative complications were glaucoma (29.3%, 12/41 eyes), corneal ulceration (24.4%, 10/36 eyes), fibrin formation (21.9%, 9/41 eyes), and silicone oil migration into the anterior chamber (19.5%, 8/41 eyes). Conclusion Post‐RR cataract surgery should be considered in dogs with vision loss from cataracts after RR. In most eyes, vision was maintained up to 1 year postoperatively.