IntroductionIt is well known that seizures and psychosis are diagnostic criteria for systemic lupus erythematosus (SLE), however, there could be many other neuropsychiatric symptoms. The American College of Rheumatology Nomenclature provides case definitions for 19 neuropsychiatric syndromes seen in SLE (NPSLE), including cognitive impairment, psychosis, mood and anxiety disorders. Lack of specific manifestations difficult diagnosis and treatment.ObjectivesTo address the diagnostic difficulties that involve the appearance of hypomanic symptoms in the course of SLE treated with high doses of corticoids in a patient with a depressive episode history.MethodDescription of case report and literature revision. We report the case of a 22-year-old woman who presented irritable mood, sexual disinhibition, insomnia and inflated self-esteem. The patient was recently diagnosed with SLE and was on treatment with 50 mg/d prednisone. She had familiar history for bipolar disorder and was taking 20 mg/d paroxetine since the last 6 months after being diagnosed with major depressive episode.ResultsWe proposed differential diagnosis between psychiatric symptoms secondary to central nervous system SLE involvement, a comorbid bipolar disorder or prednisone-induced mood symptoms. Fluctuation of hypomanic symptoms during hospitalization, poor relationship with variation in corticosteroid doses, findings on brain MRI compatible with vasculitis and positive antibodies, oriented this case to a neuropsychiatric manifestation of LES.ConclusionsWe should keep in mind that symptoms of neuropsychiatric SLE may vary from more established manifestations of NPSLE to mild diffuses ones. More studies are needed to expand knowledge in the relationship between mood disorders and neuropsychiatric SLE.Disclosure of interestThe authors have not supplied their declaration of competing interest.

IntroductionThe efficacy of electroconvulsive therapy (ECT) in the treatment of depressive episodes is well established, and so is reflected in the major guides.ObjectivesDescription of a clinical case of a patient diagnosed with major depressive episode with psychotic symptoms and obsessive compulsive disorder prevalence of compulsive acts that do not respond to drug treatment but to electroconvulsive therapy.MethodsPresentation and review of a case.ResultsA 55-year-old woman diagnosed with recurrent depressive disorder with worsening in the last 4 years.Clinical depressive Sadness, spontaneous crying in the form of access, apathy, isolation and clinofilia desires, complaints mnemonic deficits and complete anhedonia. Obsessional symptoms compulsive as more repetitive behaviors of obsessive ideas, which repeats incessantly despite checking, that does not prepare or calm. The patient has not responded to any pharmacological strategy, despite using full doses and combinations of antidepressant, but euthymics more antipsychotics (sertraline, fluoxetine, reboxetine, venlafaxine, bupropion, lithium, valproic acid, lamotrigine, risperidone, quetiapine, trifluoperazine, clotiapine). For this reason, it was decided to start treatment with ECT, progressively responds in each session, after 8 sessions the patient is euthymic, it has resumed normal activities, no obsessive or psychotic symptoms.ConclusionsIt is important to know that it is a safe technique that would save not only an economic cost, if not a personal emotional cost. It is noteworthy that more than 50% of depressed patients who respond to a course of ECT, fall between 6 and 12 months despite receiving adequate pharmacological treatment then so we will have to closely monitor the patient.Disclosure of interestThe authors have not supplied their declaration of competing interest.

IntroductionSuicidal behavior is defined as any behavior of self-harm with intent and knowledge of what is done. Suicide ranks among the 10 leading causes of death in the statistics of the world health organization.ObjectivesThe main objective of the study is to determine the sociodemographic characteristics of patients who have attempted suicide and the characteristics of this behavior.MethodsIt is a descriptive cross-sectional study.ResultsThe sample consisted of 70 patients, with a mean age of 41.17 years, most of them were women (58.5%). In relation to employment status, 31.4% were working, 21.4% unemployed, 14.3% were retired and 32.9% had other employment status. Among the characteristics of suicidal behavior characteristics, mode, forecasting rescue, previous suicidal behavior, previous outpatient follow-up and consumption of toxic evaluated. The most frequent method chosen was the voluntary intake of drugs (77.1%). The 67.1% were diagnosed with depressive disorder followed by personality disorders (20%).ConclusionsIn total there is a predominance of women in achieving some suicidal behavior, as well as a higher percentage among single, divorced or widowed (60%) versus married (40%). Also a higher percentage of patients unemployed, pensioners and others who do not receive income (68.5%) versus the occupationally active (22%). Another condition that must be evaluated in the suicide risk is having previously made a suicide attempt, in our study 54.3%. Since subjects with previous suicide attempt are four times more likely to try again. The results are also consistent with other studies that the most common disorder associated with suicide attempt is depressive disorder (67.1%).Disclosure of interestThe authors have not supplied their declaration of competing interest.

IntroductionThere are many jobs that offer advantages of treatment with long-acting injectable in psychosis.ObjectiveTo know the changes in the different variables after the start of paliperidone palmitate (PP).Material and methodWe performed a descriptive and retrospective study. Were evaluated patients who received maintenance therapy with PP during 48 months.ResultsThe sample was composed of 29 patients: 72.4% men and 27.6% women. Average age of 46.21 years. In Figures 1, 2 and 3 show data obtained in relation to compliance with treatment, relapse, maintenance dose, number of admissions and visits to emergency departments respectively.ConclusionsThe administration of PP is associated with a higher level of compliance with treatment. The patients presented a lower number of relapses, hospitalizations and visits to the emergency room. The maintenance dose more used is 150 mg.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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