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ABSTRACT

Bromoderma is a cutaneous eruption caused by the absorption of bromide. Clinical manifestations include acneiform and vegetative lesions. We report the case of an infant with bromoderma caused by the use of syrup for abdominal colic containing calcium bromide. The lesions regressed after discontinuation of the drug.

Objectives: Abnormal uterine bleeding needs careful evaluation to exclude uterine pathology, particularly endometrial cancer. The combination of Saline Infusion Sonography (SIS) and endometrial aspiration is a reliable tool for this purpose. The objective of this study was to evaluate the effect of SIS on the quality of the endometrial aspiration specimen in women with abnormal uterine bleeding by performing both examinations in one session. Methods: In this single-blind randomised controlled trial, 113 women with abnormal uterine bleeding who visited the outpatient clinic were randomly allocated either to SIS and subsequent endometrial aspiration, or to the reverse order. Both examinations were performed in one session with the same catheter. All aspiration specimens were sent to the same pathologist, who evaluated the quality of the samples.Results: The quality of the endometrial aspiration specimen was significantly better in the group of women who had aspiration before SIS, compared with women who were allocated to the reverse order (P = 0.03). Blood and mucus staining and the presence of endometrial epithelium were found to have a significant influence on the sample quality. The difference between both groups was most pronounced in women below 50 years (P = 0.02). Conclusions: This study demonstrated that the proportion of adequate specimens is higher when endometrial aspiration is performed first and subsequently SIS. Objectives: Assess differences in contrast enhancement in morphologically abnormal small ovarian masses. Method: Retrospective assessment of contrasted transvaginal sonography in women with morphologically abnormal small ovarian masses who underwent surgical removal and subsequent histologic assessment. Standard color Doppler and harmonic pulse inversion transvaginal sonography was performed using a Philips iU22 scanner with a curved 8-4 MHz transvaginal probe. Before contrast was given, power Doppler sonography was performed for detection of relatively vascular areas within tumor. After consent was obtained, patients received intravenously 0.1 µg/kg of Definity followed by 10 cc saline bolus. A three-minute segment was recorded for later analysis offline using Q-lab software. Results: As of February 2008, 17 patients with a total of 23 tumors were studied. Nine adnexal masses were primary epithelial malignant ovarian tumors, including 3 adenocarcinomas, 2 serous adenocarcinomas 2 endometroid adenocarcinomas and 2 breast cancer metastases. 14 tumors were benign, including 9 endometriomas, 2 hemorrhagic corpora lutea, 2 mucinous cystadenoma, 1 paraovarian cyst, 1 fibroma and 1 cystadenofibroma. When contrast enhancement dynamics was assessed, malignant lesions demonstrated similar time to peak (26.1 ± 6.3 sec vs 24.9 ± 7.6 sec, P = 0.7), but greater peak enhancement (23.3 ± 2.8 dB vs 12.3 ± 3.9 dB, P < 0.01), longer half wash-out time (139.9 ± 43.6 sec vs 46.3 ± 19.7 sec (P < 0.01) and greater vascular volume (2012.9 ± 532.9 sec −1 vs 523.8 ± 318 sec −1 , P < 0.01) when compared to benign les...

Phacomatosis Pigmentovascularis is a rare syndrome characterized by capillary malformation and pigmentary nevus. A case of a 2-year-old patient is reported, who presented extensive nevus flammeus and an aberrant Mongolian spot, without systemic disease, manifestations that allow us to classify this case as type IIa Phacomatosis Pigmentovascularis, according to Hasegawa's classification.