Background Burnout is characterized by physical and emotional exhaustion from long-term exposure to emotionally demanding work. Burnout affects interpersonal skills, job performance, career satisfaction, and psychological health. However, little is known about the burden of burnout among healthcare providers in sub-Saharan Africa. Methods Relevant articles were identified through a systematic review of PubMed, Web of Science (Thomson Reuters), and PsycINFO (EBSCO). Studies were selected for inclusion if they examined a quantitative measure of burnout among healthcare providers in sub-Saharan Africa. Results A total of 65 articles met our inclusion criteria for this systematic review. Previous studies have examined burnout in sub-Saharan Africa among physicians (N = 12 articles), nurses (N = 26), combined populations of healthcare providers (N = 18), midwives (N = 2), and medical or nursing students (N = 7). The majority of studies assessed burnout using the Maslach Burnout Inventory. The highest levels of burnout were reported among nurses, although all healthcare providers showed high burnout. Burnout among healthcare providers is associated with their work environments, interpersonal and professional conflicts, emotional distress, and low social support. Conclusions Available studies on this topic are limited by several methodological challenges. More rigorously designed epidemiologic studies of burnout among healthcare providers are warranted. Health infrastructure improvements will eventually be essential, though difficult to achieve, in under-resourced settings. Programs aimed at raising awareness and coping with burnout symptoms through stress management and resilience enhancement trainings are also needed.

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Over the past 20 years, the starlet sea anemone, Nematostella vectensis, a small estuarine animal, has emerged as a powerful model system for field and laboratory studies of development, evolution, genomics, molecular biology and toxicology. Here we describe how to collect Nematostella, culture it through its entire sexual life cycle and induce regeneration for the production of clonal stocks. In less than 1 h at a suitable field site, a researcher on foot can collect hundreds of individual anemones. In a few months, it is possible to establish a laboratory colony that will be reliable in generating hundreds or thousands of fertilized eggs on a roughly weekly schedule. By inducing regeneration roughly every 2 weeks, in less than 6 months, one can establish a clonal stock consisting of hundreds of genetically identical anemones. These results can be achieved very inexpensively and without specialized equipment.

Background Suicide is a leading cause of maternal death globally, and suicide prevalence rates have been shown to be increased in those with migraine. No previous study has examined the association between migraine and suicidal ideation during pregnancy. Objective To examine the association between migraine and suicidal ideation among a cohort of pregnant women. Methods A cross-sectional study was conducted among 3,372 pregnant women attending prenatal care clinics in Lima, Peru. Suicidal ideation and depression were assessed using the Patient Health Questionnaire-9 (PHQ-9) scale during early pregnancy. Migraine classification (including migraine and probable migraine) was based on International Classification of Headache Disorders (ICHD)-III beta criteria. Multivariable logistic regression analyses were performed to estimate odd ratios (OR) and 95% confidence intervals (95%CI). Results Suicidal ideation was more common among those with migraine (25.6%) as compared to those with probable migraine (22.1%, p<0.001) or non-migraineurs (12.3%, p<0.001). After adjusting for confounders, including depression, those with migraine or probable migraine had a 78% increased odds of suicidal ideation (OR=1.78; 95%CI: 1.46–2.17), as compared with non-migraineurs. Women with both migraine and depression had a 4.14-fold increased odds of suicidal ideation (OR=4.14; 95%CI: 3.17–5.42) compared to those with neither condition. Conclusion Migraine is associated with increased odds of suicidal ideation in pregnant women even when controlling for depression. These findings support the consideration of screening women with comorbid migraine and depression for suicidal behavior during pregnancy.

Parents/caregivers of transgender and/or nonbinary (TNB) youth (those who identify with a different gender than the gender typically associated with their assigned sex) may experience secondary stigma related to their child’s TNB identity. However, parent/caregiver support is critical for TNB youth’s mental health. This study explored attitudes and challenges faced by parents/caregivers of TNB youth. Data were from 27 parents/caregivers of TNB youth who completed an anonymous online survey with qualitative and quantitative measures. Qualitative data were analyzed using immersion/crystallization and thematic analysis approaches. Six themes were developed from the data: TNB youth individual characteristics/experiences, societal and other external factors affecting parent/caregivers’ future outlook, TNB identity development and transition, TNB-related social and institutional interactions, parent/caregivers’ supportive cognitions and behaviors, and parent/caregivers’ challenging cognitions. Findings from this study can inform efforts to support parents/caregivers of TNB youth, which can ultimately support the well-being of TNB youth themselves.