Severe gout is associated with poor HRQOL and disability, especially for patients who experience more gout flares and have a greater number of involved joints. Subject perceptions of gout-related functioning and pain severity appear to be highly sensitive indicators of HRQOL and disability.
Discussion and voting at OMERACT 9 confirmed 5 essential domains for outcomes of acute gout: pain, joint swelling, joint tenderness, patient global assessment and activity limitations. For studies in chronic gout 7 essential domains are: serum urate, acute gout attacks, tophus burden, health-related quality of life, activity limitations, pain, and patient global assessment. Implications of patient perspectives, discretionary domains for specific studies, measurement instruments and a possible responder index are under study.
Background Little is known about patients with gout with regards to the use of complimenatry and non-pharmacological approaches to treatment of gout. Qualitative work has shown that patients are interested in these treatment options. To our knowledge, there are no other studies of characteristics of patients who use supplements for gout. Objectives To assess the frequency of use of urate-lowering therapy (ULT) and natural supplements including cherry extract by patients with gout. Methods A pop-up on the website the Gout and Uric Acid Education Society's website () informed people about the optional survey from 11/20/2013 to 01/15/14. The survey queried people regarding the use of ULT and supplements. Results Of the 162 survey respondents, 121 (74%) reported gout. Mean age of survey responders was 55.4 years (standard deviation, 14.5), 69% were men and 71% were White. Gout disease duration was ≤1 year in 29%, 1-5 years in 22%, 5-10 years in 22% and >10 years in 21% (missing, 6%). Gout flares were common, with 89% with ≥1 gout flare in the last month (i.e. >3/year). 51% had been prescribed allopurinol of febuxostat, 78% missed it for <7 days/month. 42% participants were taking cherry extract or juice and 21% were taking other natural supplements. Conclusions Use of cherry extract and natural supplements is not uncommon in patients with gout. Only half of all gout patients were prescribed ULT by their providers. Acknowledgements We thanks gouteducation.org for displaying our survey. Disclosure of Interest J. Singh Grant/research support: Takeda, Savient, Consultant for: Takeda, Savient, Novartis, Allergan, Regeneron, A. Bharat: None declared, L. Edwards: None declared DOI 10.1136/annrheumdis-2014-eular.4846
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