Objective: To evaluate the role of CRP in clinical outcome in patient of PPROM. Methodology: A prospective study was done on 90 cases with PPROM and raised CRP (>9mg/l) and 90 cases of control group with PPROM and normal CRP (<9mg/l). All mothers and babies were observed from the time of admission to the time of discharge. Results: The incidence of chorioamnionitis was seen to be higher in the cases with raised CRP. The socioeconomic status, parity were found to have an important role in patients developing chorioamnionitis. The sensitivity of the test (raised CRP) in causing clinical chorioamnionitis is more than 90% and specificity in 50%. Odds ratio is 12.5 i.e cases (raised CRP) have 12.5 times more chances of having clinical chorioamnionitis than those of controls (normal CRP). Conclusion: In cases of PPROM, raised CRP is a predictor of clinical chorioamnionitis.