The main objective of this study was to determine the prevalence of Irritable Bowel Syndrome (IBS) and its associated factors among University students in Saudi Arabia, as little is known about this issue in our country. This cross-sectional study was conducted between 13 March and 21 May of the Academic Year 2017-2018 at Jazan University, Saudi Arabia, involving a random sample of 890 students, selected using the stratified multistage method. IBS prevalence was determined using the Rome IV diagnostic Criteria. The overall prevalence of IBS was 8.8%. According to the results of the multivariate logistic regression, the most important independent predictors of IBS were being a student in a medical college (OR = 10.42; 95%CI: 3.45-31.51) and a scientific college (OR = 5.16; 95%CI: 1.64-16.22), cigarettes smoking (OR = 2.74; 95%CI: 1.24-6.07), emotional stress (OR = 2.53; 95%CI: 1.28-5.00), and food intolerance (OR = 2.15; 95%CI: 1.11-4.16). The present study revealed a prevalence rate of 8.8%. The main predictors of IBS were being a medical student, a scientific college student, cigarette smoker, and having emotional stress and food intolerance. No significant association was found between IBS and anxiety and depression.

Objective: To investigate the relation between dyslipidemia and insulin resistance where it is one of the metabolicdisorders in patients with type-ΙΙ diabetes mellitus and compare the results with the control group.Methodology: Blood samples were collected from (35) patients with type-ΙΙ diabetes mellitus, besides (35) healthyindividuals as a control group were enrolled in this study. The age of all subjects range from (20-50). Serum wasused in determination of glucose, insulin, lipid profile (cholesterol (Ch), triglyceride (TG), high-density lipoprotein(HDL-Ch), low-density lipoprotein (LDL-Ch) and very low-density lipoprotein (VLDL), for patients and controlgroups. Insulin resistance (IR) was calculated according to homeostatic model (HOMA-IR).Results: The results revealed a statistically significant elevation levels (P<0.001) in each of glucose, insulin, insulinresistance, Ch, TG, LDL-Ch, and VLDL, except HDL-Ch which was decreased in all patients group comparing withcontrol group.Recommendations: To study the Inflammatory factors and leptin and their relation to insulin resistance in type-ΙΙDM.

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Chronic renal failure (CRF) affects thyroid function in multiple ways, including low circulating thyroid hormone concentration, altered peripheral hormone metabolism, disturbed binding to carrier proteins, possible reduction in tissue thyroid hormone content, and increased iodine store in thyroid glands.The target of study is to find a relationship between chronic renal failure and thyroid function.In addition, we tried to study the effect of CRF on serum creatinine dependent on the level of thyroid hormones (T3 and T4) and thyroid stimulating hormones(TSH). Forty patients with chronic renal failure (20 male, 20 female) were enrolled in this study in addition to forty healthy individual as control group (20 male, 20 female). The age ranged from (25 -65) years. T4, T3, TSH, urea, uric acid and creatinine were measured in each of the two groups. The results revealed statistically significant reduction in T3 and T4 while there is elevation in TSH, urea,uric acid and creatinine in the patients group compared to the control group. Key word : Chronic Renal Failure,Thyroid Hormones.

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