and edited the article. V.N.L. and N.T.N. equally designed and conducted the experiment. N.Q.D. and V.N.L. studied scientific literature about the topic. All authors read and approved the final manuscript. This study complied with the Declaration of Helsinki in relation to medical research involving human subjects and got consent from the Research Ethics Committee of the 108 Institute of Clinical Medical and Pharmaceutical Sciences. Informed consent was obtained from all individual participants included in the study. All patients provided written consent for publication of their photographs and surgery outcomes.

Anterolateral thigh flap (ALT flap) is first found and used by Song in 1984. Classified in the perforator type flaps, ALT flaps is blood supplied by the perforators of the descending branch of the lateral circumflex thigh artery. The flap is the first of choice in many cases, those need a large soft tissue for reconstruction, especially in the cervico facial area thanks to many advantages of the flap: constants and relievable anatomic structure, large blood supply, flexible in use as well as other advantages. From 9.2016 to 10. 2020, 26 ALT flaps are dissected in fresh and Formalin cavades of mature Viet people for the anatomic research and 34 ALT flaps used for patients with soft tissue defects in cervicofacial area. The outcome is considerable with the main following conclusions: - ALT flap is constant and reliable in anatomy. - The flap is harvested relatively easy in clinical practice. - The use of the ALT flap is flexible with good result in reconstruction of soft tissue defects in cervico facial area.

Large cell undifferentiated carcinoma of parotid gland is a rare disease of salivary gland cancer accounting about 1%, however, it has high malignancy and very poor prosgnosis. We report a clinical case with symptoms of left parotid gland tumor, rapid growth , invasive skin and superficial ulceration . The differential diagnosis is difficult between parotid adenocarcinoma and skin cancer or metastatic cervical lymphoma. The patient underwent extensive surgical resection of the lesion, radical cervical lymphadenectomy, and reconstruction with local flaps. The definitive diagnosis after surgery: large cell undifferentiated carcinoma of the left parotid gland stage IV (pT4aN0M0). The patient did not receive early radiation therapy, therefore local recurrence and distal metastasis, and death 6 months after surgery.

Target: Analyze the factors related to the treatment results of diffuse facial inflammation through 2 cases to draw experience in diagnosis and management attitude. Objects - Methods: 2 patients diagnosed with diffuse inflammation in the jaw area were treated at the Faculty of Facial Surgery and Plastic - 108 Centre Military Hospital on December 2019. Method: Description of a cluster of diseases. Results - Discussion:  Diagnosis of diffuse inflammation in the jaw area is based on clinical and imaging diagnosis. Diagnostic imaging methods can use ultrasound, computed tomography, magnetic resonance. Computer tomography is often used because of the rapid duration of the scan, assessment of soft inflammatory lesions, and to assess bone and tooth damage. Computerized tomography image said: (1) edema of the organization, the location, size of purulent foci, the direction of spread of inflammation, the appearance of air bubbles in the organization; (2) degree of tamponade of the airway; (3) condition of inflammation spread to the mediastinum, pleura; (4) the source of the infection can be teeth. Diffuse inflammation in the jaw area progresses rapidly, with a high risk of death. Treatment should be aggressive, comprehensive based on factors: early diagnosis, airway control, adequate purulent drainage enlargement surgery, high-dose antibiotics, cause tooth extraction. Conclude: Diffuse inflammation in the jaw area is an emergency disease, need early diagnosis and surgery, incision to remove the pus satisfactorily at the beginning, Combined with systemic antibiotics, treatment for other associated systemic disorders will bring good results, shorten treatment time, reduce the number of surgeries as well as treatment costs, reduce the risk of death.

Background: Hyaluronic acid (HA) fillers for aesthetic are generally considered safe and the use of dermal fillers for soft tissue augmentation has become a very popular technique in aesthetic practices. Dermal fillers temporarily remove the appearance of rhytids and reduce the depth of skin folds. This is one of the most effective method for facial improvement used in Viet Nam nowadays.  However, complications such as skin necrosis, blind... may happen and hence any filler injection practitioner need to be aware of such side effects, contraindications and precaution to be adopted while using fillers. Even with the most experienced of injectors, adverse effects can and do occur ranging from mild bruising to severe injection necrosis. Aims: HA filler injectors should be able to prevent and treat the severe complication of skin necrosis and detect impending necrosis after injection of a augmentation filler. Materials and Methods: Cases report of 3 patients who were HA filler injection for nose augmentation and had suffered from skin necrosis. These patients were followed for 3-6 months from time of injection of hyaluronic acid filler to complete healing of wound. Results: Complete wound healing were achieved with early recognition and institution of treatment, surgical procedures applied in some severe cases. The functional of the noses are remained but  most of the patients have bad scar on the nose. Discussion: We review cases report of injection necrosis and methods used to prevent and treat this complication. Conclusion: Early recognition of vascular necrosis with specific protocol for treatment after injection necrosis with hyaluronic acid fillers improves the outcome of wound healing.