Elephantiasis nostras verrucosa (ENV) is the most severe form of chronic non-filarial lymphedema that leads to disfiguration of body parts. Multiple topical and surgical treatments have been typically used with high relapse rates and local complications. In this context, CO2 laser emerges as a new well-tolerated and effective treatment option. We report two cases of long-term evolution of elephantiasis nostras verrucosa recalcitrant to topical therapy and successfully treated with CO2 laser. Both of them were septuagenarians with personal history of obesity and suffered from lower extremities edema due to heart failure in one case, and due to chronic venous insufficiency in the other. We describe the procedure, the results and the advisable maintenance for preventing recurrence in this difficult to treat and chronic condition.

Alopecia after mesotherapy with dutasteride is an extremely rare complication. Dutasteride is a second-generation 5a-reductase enzyme inhibitor that decreases serum dihydrotestosterone levels by 90%. It inhibits both type 1 and 2 enzymes, whereas finasteride inhibits only type 2. Mesotherapy with dutasteride is a novel treatment for hair fall which involves microinjection of the drug into the dermis with negligible systemic absorption. Frequent mild transitory side effects in the site of injection are described in medical literature, but few cases of secondary alopecia have been reported. This stands out given that mesotherapy is becoming such an increasingly common procedure with a great number of patients treated with this technique. We present 2 cases of patchy alopecia after mesotherapy with dutasteride in a male and a female with androgenetic alopecia. One of them developed skin atrophy on the affected areas without improvement at short term follow-up. These cases highlight the possible paradoxical side effects of mesotherapy as a therapeutic technique for hair loss.

No abstract

No abstract

Background: Seabather's Eruption is an acute dermatitis allegedly produced by larvae from of the thimble jellyfish. Most of the published cases are originated in the Caribbean Sea. We present two cases of patients with cutaneous lesions located on the parts covered by the swimsuit that appeared after having been in contact with the sea water of the Cantabrian Sea beaches in Northern Spain. Methods: Anamnesis, physical exam, cutaneous biopsy, epicutaneous and blood tests were carried out. Results: According to the clinical evolution and the complementary tests, the possibility of contact dermatitis was dismissed, as well as other sea dermatosis, and Sea bather's Eruption was stated as the principal diagnosis suspect. Conclusions: We suggest that increasing temperatures in the last few years in the Cantabrian Sea could facilitate the presence of this dermatosis. We consider the seabather's eruption knowledge of great interest, not only for the imported cases but the possibility of reporting a higher number of native cases in the coming years.